Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.40 |
| ▸ | PDE2A | O00408 | 3/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21436206 | 1.00 | MAOA (0.41) | MAOAMAOBKDM1ASLC6A3SLC6A4 | |
| SCHEMBL21436156 | 1.00 | MAOA (0.41) | MAOAMAOBKDM1ASLC6A3SLC6A4 | |
| SCHEMBL21436185 | 1.00 | MAOA (0.41) | MAOAMAOBKDM1ASLC6A3SLC6A4 | |
| Hydrochloric Acid SCHEMBL21436148 | 0.99 | SLC6A3 (0.40) | MAOAMAOBKDM1ASLC6A3SLC6A4 | |
| Hydrochloric Acid SCHEMBL28495083 | 0.99 | SLC6A3 (0.40) | MAOAMAOBKDM1ASLC6A3SLC6A4 | |
| Hydrochloric Acid SCHEMBL21436246 | 0.99 | SLC6A3 (0.40) | MAOAMAOBKDM1ASLC6A3SLC6A4 | |
| Oxalic Acid SCHEMBL21436257 | 0.95 | SLC6A3 (0.38) | MAOAMAOBKDM1ASLC6A3SLC6A4 | |
| Sulfuric Acid SCHEMBL21436150 | 0.95 | SLC6A3 (0.38) | MAOAMAOBKDM1ASLC6A3SLC6A4 | |
| SCHEMBL21436239 | 0.92 | SLC6A3 (0.41) | MAOAMAOBKDM1ASLC6A3SLC6A4 | |
| SCHEMBL21436180 | 0.87 | KDM1A (0.46) | KDM1ASLC6A3SLC6A4SLC6A2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3778579-A1 | AROMATIC COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Jianhe Pharmaceutical & Technology Co. Ltd. (CN) | 2021-02-17 | — | — | EP | disclosed |