SCHEMBL23004665

SCHEMBL23004665

C#Cn1c(=O)n(CC)c(=O)n(CC)c1=O

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3A P49840 4/20 0.35
GSK3B P49841 4/20 0.35
ALDH1A1 P00352 2/20 0.33
KDM4E B2RXH2 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
GFER P55789 1/20 0.33
ADORA2A P29274 2/20 0.32
ADORA2B P29275 1/20 0.32
CYP1A2 P05177 1/20 0.31
F2 P00734 1/20 0.31
ELANE P08246 1/20 0.31
CTSG P08311 1/20 0.31
CTRC Q99895 1/20 0.31
RGS4 P49798 1/20 0.31
RGS8 P57771 1/20 0.31
SIRT2 Q8IXJ6 1/20 0.30
SIRT1 Q96EB6 1/20 0.30
SIRT3 Q9NTG7 1/20 0.30
SIRT5 Q9NXA8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22899038 0.95 GSK3A (0.35) GSK3AGSK3BF2ELANECTSG
SCHEMBL22899014 0.88
SCHEMBL22899087 0.79 RGS4 (0.44) GSK3BGAAMAPTADORA2AADORA2B
SCHEMBL22899036 0.77 GSK3A (0.34) GSK3AGSK3BKDM4EADORA2AADORA2B
SCHEMBL21531890 0.76 ADORA2B (0.38) GSK3AGSK3BALDH1A1KDM4EGAA
SCHEMBL22899015 0.76 ADORA2B (0.38) GSK3AGSK3BALDH1A1KDM4EGAA
SCHEMBL22898925 0.74 RGS4 (0.44) GSK3BGAAMAPTADORA2AADORA2B
SCHEMBL22899042 0.73 PDE4A (0.32) ADORA2AADORA2BCYP1A2PDE4APDE4B
SCHEMBL17341693 0.71 ADORA2B (0.34) ADORA2B
SCHEMBL20392162 0.68 RGS4 (0.53) GSK3AGSK3BALDH1A1ADORA2AADORA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3780226-B1 NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE BATTERY MITSUBISHI CHEM CORP (JP) 2022-05-11 EP disclosed
EP-3780226-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE BATTERY Mitsubishi Chemical Corporation (JP) 2021-02-17 EP disclosed