Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 10/20 | 0.66 |
| ▸ | TYMS | P04818 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MTHFD1 | P11586 | 1/20 | 0.37 |
| ▸ | MTHFD2 | P13995 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23005146 | 1.00 | FPR2 (0.66) | FPR2TYMSCA2CA1KDM4E | |
| SCHEMBL23005149 | 0.82 | FPR2 (0.65) | FPR2KDM4EHPGDFOLH1GAA | |
| SCHEMBL23005148 | 0.82 | FPR2 (0.65) | FPR2KDM4EHPGDFOLH1GAA | |
| SCHEMBL23005206 | 0.81 | FPR2 (0.65) | FPR2CA2CA1KDM4EHPGD | |
| SCHEMBL23005205 | 0.81 | FPR2 (0.65) | FPR2CA2CA1KDM4EHPGD | |
| SCHEMBL23030265 | 0.81 | FPR2 (0.46) | FPR2KDM4EHPGD | |
| SCHEMBL23005180 | 0.80 | FPR2 (0.59) | FPR2CA2CA1KDM4EHPGD | |
| SCHEMBL23005181 | 0.80 | FPR2 (0.59) | FPR2CA2CA1KDM4EHPGD | |
| SCHEMBL21494614 | 0.80 | FPR2 (1.00) | FPR2MTHFD1MTHFD2 | |
| SCHEMBL21494612 | 0.80 | FPR2 (1.00) | FPR2MTHFD1MTHFD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112218858-B | 2, 6-Diamino-3, 4-dihydropyrimidin-4-one derivatives and their use in therapy | 托马斯·黑勒戴药物研究基金会 | 2024-06-18 | — | — | CN | disclosed |
| EP-3781554-B1 | 2,6-DIAMINO-3,4-DIHYDROPYRIMIDIN-4-ONE DERIVATIVES AND USE THEREOF IN THERAPY | THOMAS HELLEDAYS STIFTELSE FOER MEDICINSK FORSKNING (SE) | 2023-06-28 | — | — | EP | disclosed |
| US-20210052587-A1 | 2,6-DIAMINO-3,4-DIHYDROPYRIMIDIN-4-ONE DERIVATIVES AND USE THEREOF IN THERAPY | MEDICINSK FORSKNING (SE) | 2021-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210052587-A1 | 2,6-DIAMINO-3,4-DIHYDROPYRIMIDIN-4-ONE DERIVATIVES AND USE THEREOF IN THERAPY | IL2, THPO, IL6 | FPR2 435/4885TYMS 280/4885CA2 2254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.