SCHEMBL23005388

SCHEMBL23005388

O=C1CC(C(=O)O)N(c2ncccc2Cl)N1

nearest known ligand 0.42

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MALT1 Q9UDY8 6/20 0.42
SMN1; SMN2 Q16637 1/20 0.38
TRPA1 O75762 2/20 0.37
TRPV1 Q8NER1 1/20 0.35
HSD11B1 P28845 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12528898 0.88 MALT1 (0.40) MALT1TRPA1TRPV1HSD11B1
SCHEMBL3740818 0.85 MALT1 (0.40) MALT1TRPA1TRPV1
SCHEMBL10300142 0.85 MALT1 (0.37) MALT1TRPA1TRPV1HSD11B1
SCHEMBL29661868 0.82 CYP2C19 (0.44) MALT1HSD11B1
SCHEMBL29661865 0.82 CYP2C19 (0.44) MALT1HSD11B1
SCHEMBL30663927 0.82 MALT1 (0.39) MALT1TRPA1TRPV1
SCHEMBL951112 0.82 CYP2C19 (0.44) MALT1HSD11B1
SCHEMBL23012996 0.82 MALT1 (0.39) MALT1TRPA1TRPV1
Pyridine SCHEMBL26906528 0.80 MALT1 (0.36) MALT1TRPA1TRPV1
SCHEMBL21645299 0.80 HSD11B1 (0.44) MALT1TRPV1HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102584694-A Preparation methods for important intermediates of anthranilic diamide compound UNIV EAST CHINA SCIENCE & TECH 2012-07-18 CN claimed
CN-114057687-B Preparation method of pyridyl pyrazolone carboxylic ester compound 沈阳中化农药化工研发有限公司 2023-11-14 CN disclosed
CN-116940560-A Process for producing 3-bromo-1- (3-chloropyridin-2-yl) -1H-pyrazole-5-carboxylic acid ester 石原产业株式会社 2023-10-24 CN disclosed
EP-4003962-A1 PROCESS FOR SYNTHESIS OF PYRAZOLIDINONE COMPOUNDS Gharda Chemicals Limited (IN) 2022-06-01 EP disclosed
WO-2021033166-A1 PROCESS FOR SYNTHESIS OF PYRAZOLIDINONE COMPOUNDS GHARDA CHEMICALS LIMITED (IN) 2021-02-25 WO disclosed
WO-2021033165-A1 PROCESS FOR SYNTHESIS OF PYRAZOLIDINONE COMPOUNDS GHARDA CHEMICALS LIMITED (IN) 2021-02-25 WO disclosed
WO-2021033165-A1 PROCESS FOR SYNTHESIS OF PYRAZOLIDINONE COMPOUNDS GHARDA CHEMICALS LIMITED (IN) 2021-02-25 WO disclosed
CN-108084152-B Bisamide compound and synthesis method and application thereof 浙江工业大学 2020-06-30 CN disclosed
CN-104496901-B The manufacture method of anthranilamide compound ISHIHARA SANGYO KAISHA, LTD. (JP) 2016-05-25 CN disclosed
CN-102285963-B 3-methoxy pyrazolecarboxamide compound and application thereof SINOCHEM CORP 2014-04-09 CN disclosed
CN-102285971-A Pyrazolyl quinazolinone compound and application thereof 2011-12-21 CN disclosed
CN-101945861-A A kind of preparation method of benzamide compound SINOCHEM CORP 2011-01-12 CN disclosed
CN-101298451-A Benzamide compounds and use thereof SINOCHEM CORP (CN) 2008-11-05 CN disclosed
CN-101287721-A Hydrazide compound and pesticidal use of the same SUMITOMO CHEMICAL CO (JP) 2008-10-15 CN disclosed
CN-101134755-A Quinazoline(di) ones for invertebrate pest control DU PONT (US) 2008-03-05 CN disclosed
CN-100349890-C Quinazolinone (di) ones for controlling invertebrate pests DU PONT (US) 2007-11-21 CN disclosed
CN-101039929-A Novel anthranilamides for controlling invertebrate pests DU PONT (US) 2007-09-19 CN disclosed
CN-1307161-C Substituted dihydro-3-halo-1H-pyrazole-5-carboxylic acid esters, their preparation and use DU PONT (US) 2007-03-28 CN disclosed
CN-1620450-A Quinazolinone (di) ones for controlling invertebrate pests DU PONT (US) 2005-05-25 CN disclosed
CN-1541206-A Substituted dihydro 3-hylo-1H-pyrazoloe-5-carboxylates their prepn. and use ��Ļ���Ű˾ 2004-10-27 CN disclosed