Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 10/20 | 0.40 |
| ▸ | RBP4 | P02753 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23012996 | 0.87 | MALT1 (0.39) | MALT1TRPV1TRPA1 | |
| SCHEMBL29661868 | 0.87 | CYP2C19 (0.44) | MALT1 | |
| SCHEMBL951112 | 0.87 | CYP2C19 (0.44) | MALT1 | |
| SCHEMBL30663927 | 0.87 | MALT1 (0.39) | MALT1TRPV1TRPA1 | |
| SCHEMBL29661865 | 0.87 | CYP2C19 (0.44) | MALT1 | |
| SCHEMBL12528898 | 0.86 | MALT1 (0.40) | MALT1TRPV1TRPA1 | |
| SCHEMBL23005388 | 0.85 | MALT1 (0.42) | MALT1TRPV1TRPA1 | |
| SCHEMBL29661853 | 0.84 | NPFFR1 (0.37) | MALT1TRPV1TRPA1 | |
| Acetonitrile SCHEMBL28442107 | 0.83 | CYP2C19 (0.41) | MALT1 | |
| Pyridine SCHEMBL26906528 | 0.83 | MALT1 (0.36) | MALT1TRPV1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7442799-B2 | reacting succinic acid derivatives with substituted hydrazines in presence of acid scavengers and solvents, to form chemical intermediates for benzoxazinones; cyclization | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-10-28 | — | — | US | claimed |
| WO-2023110710-A1 | METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR | SYNGENTA CROP PROTECTION AG (CH) | 2023-06-22 | — | — | WO | disclosed |
| CN-106831705-B | Synthesis method of pyridyl pyrazolidone carboxylic ester compound | 江苏扬农化工集团有限公司 | 2021-02-19 | — | — | CN | disclosed |
| EP-2251336-A1 | Hydrazide compounds as intermediates of pesticides | Sumitomo Chemical Company, Limited (JP) | 2010-11-17 | — | — | EP | disclosed |
| US-7834186-B2 | Preparation and use of 2-substituted-5-oxo-3-pyrazolidinecarboxylates | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-11-16 | — | — | US | disclosed |
| CN-100522958-C | Preparation and use of 2-substituted-5-oxo-3- pyrazolidinecarboxylates | DU PONT (US) | 2009-08-05 | — | — | CN | disclosed |
| US-20090036686-A1 | PREPARATION AND USE OF 2-SUBSTITUTED-5-OXO-3-PYRAZOLIDINECARBOXYLATES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-02-05 | — | — | US | disclosed |
| US-7442799-B2 | reacting succinic acid derivatives with substituted hydrazines in presence of acid scavengers and solvents, to form chemical intermediates for benzoxazinones; cyclization | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-10-28 | — | — | US | disclosed |
| US-20070021468-A1 | Preparation and use of 2-substituted-5-oxo-3-pyrazolidinecarboxylates | FMC CORPORATION | 2007-01-25 | — | — | US | disclosed |
| EP-1606276-B1 | PREPARATION AND USE OF 2-SUBSTITUTED-5-OXO-3- PYRAZOLIDINECARBOXYLATES | DU PONT (US) | 2006-09-27 | — | — | EP | disclosed |
| CN-1764658-A | Preparation and use of 2-substituted-5-oxo-3- pyrazolidinecarboxylates | DU PONT (US) | 2006-04-26 | — | — | CN | disclosed |
| EP-1606276-A1 | PREPARATION AND USE OF 2-SUBSTITUTED-5-OXO-3- PYRAZOLIDINECARBOXYLATES | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2005-12-21 | — | — | EP | disclosed |
| WO-2004087689-A1 | PREPARATION AND USE OF 2-SUBSTITUTED-5-OXO-3- PYRAZOLIDINECARBOXYLATES | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2004-10-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021468-A1 | Preparation and use of 2-substituted-5-oxo-3-pyrazolidinecarboxylates | HRH2, OGDH, HRH1 | MALT1 4221/4885RBP4 2845/4885TRPV1 4078/4885 |
| US-20090036686-A1 | PREPARATION AND USE OF 2-SUBSTITUTED-5-OXO-3-PYRAZOLIDINECARBOXYLATES | HRH2, HRH3, HRH1 | MALT1 4197/4885RBP4 2981/4885TRPV1 3854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.