Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20939184 | 0.80 | MAP3K14 (0.33) | MAP3K14 | |
| SCHEMBL20939543 | 0.78 | MAP3K14 (0.33) | MAP3K14 | |
| SCHEMBL22421146 | 0.78 | MAP3K14 (0.40) | MAP3K14 | |
| SCHEMBL12997660 | 0.74 | KDM4E (0.35) | — | |
| SCHEMBL23005401 | 0.70 | MAP3K14 (0.31) | MAP3K14 | |
| SCHEMBL20939798 | 0.70 | MAP3K14 (0.34) | MAP3K14 | |
| SCHEMBL18655528 | 0.69 | NPSR1 (0.33) | — | |
| SCHEMBL17433052 | 0.67 | HRH3 (0.32) | — | |
| SCHEMBL16559399 | 0.66 | KMT2A (0.36) | — | |
| SCHEMBL22421148 | 0.66 | ALDH1A1 (0.33) | MAP3K14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3778603-A1 | 7,8-DIHYDRO-3H-PYRAZINO[1,2-B]PYRIDAZINE-3,5(6H)-DIONE COMPOUNDS AND USES THEREOF | Janssen BioPharma, Inc. (US) | 2021-02-17 | — | — | EP | disclosed |