Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.33 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23005638 | 0.91 | AAK1 (0.42) | AAK1OPRM1IDO1GRIN2BSIRT2 | |
| SCHEMBL23005558 | 0.87 | AAK1 (0.43) | AAK1OPRM1IDO1SIRT2SIRT1 | |
| SCHEMBL23005674 | 0.85 | SIRT2 (0.35) | OPRM1SIRT2SIRT1F2F10 | |
| SCHEMBL23005709 | 0.84 | AAK1 (0.45) | AAK1IDO1GRIN2BHSD17B10F2 | |
| SCHEMBL23005732 | 0.82 | OPRM1 (0.35) | OPRM1IDO1GRIN2BHSD17B10F2 | |
| SCHEMBL23005797 | 0.78 | OPRM1 (0.35) | OPRM1HSD17B10F2F10PLG | |
| SCHEMBL23005561 | 0.74 | ALDH1A1 (0.40) | AAK1IDO1GRIN2BSIRT2SIRT1 | |
| SCHEMBL23005795 | 0.73 | OPRM1 (0.35) | OPRM1SIRT2SIRT1HSD17B10F2 | |
| SCHEMBL23005733 | 0.69 | OPRM1 (0.40) | OPRM1POLBALOX5 | |
| SCHEMBL22992487 | 0.69 | OPRM1 (0.43) | OPRM1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021027724-A1 | IMMUNOMODULATOR | 成都先导药物开发股份有限公司 | 2021-02-18 | — | — | WO | disclosed |