Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 20/20 | 0.38 |
| ▸ | TGFBR2 | P37173 | 9/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29366025 | 0.89 | TGFBR1 (0.39) | TGFBR1TGFBR2MAPK14 | |
| SCHEMBL23007882 | 0.89 | TGFBR1 (0.39) | TGFBR1TGFBR2MAPK14 | |
| SCHEMBL29363762 | 0.88 | TGFBR1 (0.39) | TGFBR1TGFBR2 | |
| SCHEMBL23007901 | 0.88 | TGFBR1 (0.39) | TGFBR1TGFBR2 | |
| SCHEMBL23007694 | 0.88 | TGFBR1 (0.35) | TGFBR1TGFBR2MAPK14 | |
| SCHEMBL29366436 | 0.88 | TGFBR1 (0.46) | TGFBR1TGFBR2 | |
| SCHEMBL23008003 | 0.88 | TGFBR1 (0.46) | TGFBR1TGFBR2 | |
| SCHEMBL23007706 | 0.87 | TGFBR1 (0.35) | TGFBR1TGFBR2 | |
| SCHEMBL23008014 | 0.87 | TGFBR1 (0.38) | TGFBR1TGFBR2 | |
| SCHEMBL23008013 | 0.87 | TGFBR1 (0.38) | TGFBR1TGFBR2MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021027594-A1 | IMIDAZOLOPYRIMIDINE COMPOUNDS COMPRISING FUSED RING GROUP, PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2021-02-18 | — | — | WO | disclosed |