Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 3/20 | 0.34 |
| ▸ | TLR2 | O60603 | 1/20 | 0.33 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.33 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL548215 | 0.82 | KMT2A (0.48) | GABRA1GABRB2MEN1LMNATHRB | |
| SCHEMBL11504593 | 0.80 | GABRA1 (0.66) | GABRA1GABRB2MEN1LMNATHRB | |
| SCHEMBL15789377 | 0.80 | GABRA1 (0.46) | GABRA1GABRB2MEN1LMNATHRB | |
| SCHEMBL1970798 | 0.78 | GABRA1 (0.56) | GABRA1GABRB2ELANECTSGCYP2A6 | |
| SCHEMBL954574 | 0.76 | GABRA1 (0.54) | GABRA1GABRB2MEN1LMNAKMT2A | |
| SCHEMBL10587634 | 0.75 | LMNA (0.42) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL2287987 | 0.74 | GABRA1 (0.40) | GABRA1GABRB2MEN1LMNATHRB | |
| SCHEMBL11142154 | 0.73 | KMT2A (0.50) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL26606754 | 0.73 | ERN1 (0.31) | GABRA1GABRB2ALDH1A1ERN1SMN1; SMN2 | |
| SCHEMBL953300 | 0.72 | GABRA1 (0.48) | GABRA1GABRB2MEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021030703-A1 | DEPALMITOYLATING COMPOSITIONS AND THE USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-02-18 | — | — | WO | disclosed |