Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 15/20 | 0.43 |
| ▸ | TGFBR2 | P37173 | 9/20 | 0.43 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29366477 | 1.00 | TGFBR1 (0.43) | TGFBR1TGFBR2IRAK4CYP2A6MAPK14 | |
| SCHEMBL23007796 | 0.84 | TGFBR1 (0.36) | TGFBR1TGFBR2IRAK4MAPK14 | |
| SCHEMBL29363330 | 0.84 | TGFBR1 (0.36) | TGFBR1TGFBR2IRAK4MAPK14 | |
| SCHEMBL29366036 | 0.83 | TGFBR1 (0.59) | TGFBR1TGFBR2 | |
| SCHEMBL23007883 | 0.83 | TGFBR1 (0.59) | TGFBR1TGFBR2 | |
| SCHEMBL23007812 | 0.83 | IRAK4 (0.36) | TGFBR1TGFBR2IRAK4 | |
| SCHEMBL29366055 | 0.83 | IRAK4 (0.36) | TGFBR1TGFBR2IRAK4 | |
| SCHEMBL23007811 | 0.82 | TGFBR1 (0.35) | TGFBR1TGFBR2CYP2A6PDE10A | |
| SCHEMBL29366337 | 0.82 | TGFBR1 (0.35) | TGFBR1TGFBR2CYP2A6PDE10A | |
| SCHEMBL23007868 | 0.79 | TGFBR1 (0.48) | TGFBR1TGFBR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021027594-A1 | IMIDAZOLOPYRIMIDINE COMPOUNDS COMPRISING FUSED RING GROUP, PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2021-02-18 | — | — | WO | disclosed |