SCHEMBL23008684

SCHEMBL23008684

C=C/C(=C\C=C/C)c1ccccn1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.42
CES2 O00748 1/20 0.40
CES1 P23141 1/20 0.40
KDM4E B2RXH2 5/20 0.40
LMNA P02545 3/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
NAPRT Q6XQN6 1/20 0.39
P4HTM Q9NXG6 1/20 0.39
KMT2A Q03164 3/20 0.36
MAPK1 P28482 1/20 0.36
RAB9A P51151 7/20 0.35
SMN1; SMN2 Q16637 4/20 0.35
HTT P42858 2/20 0.35
OPRK1 P41145 2/20 0.35
PTBP1 P26599 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
GSK3B P49841 1/20 0.35
NPC1 O15118 4/20 0.35
PKM P14618 3/20 0.35
MAPT P10636 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13556893 0.86 ALDH1A1 (0.40) ALDH1A1CES2CES1KDM4ELMNA
SCHEMBL19068888 0.85 CES2 (0.41) ALDH1A1CES2CES1KDM4ELMNA
SCHEMBL19085493 0.85 ALDH1A1 (0.43) ALDH1A1CES2CES1KDM4ELMNA
SCHEMBL13488558 0.84 ALDH1A1 (0.48) ALDH1A1CES2CES1KDM4ELMNA
SCHEMBL24704614 0.83 ALDH1A1 (0.42) ALDH1A1CES2CES1KDM4ELMNA
SCHEMBL27611283 0.82 CES2 (0.45) ALDH1A1CES2CES1KDM4ELMNA
SCHEMBL24042309 0.79
SCHEMBL13186864 0.79 ALDH1A1 (0.44) ALDH1A1CES2CES1KDM4ELMNA
SCHEMBL26707241 0.78 KMT2A (0.49) ALDH1A1CES2CES1KDM4ELMNA
SCHEMBL26707219 0.78 KDM4E (0.32) ALDH1A1KDM4ERAB9ASMN1; SMN2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3425693-B1 METHOD FOR PRODUCING AN ORGANIC LIGHT-EMITTING DIODE UNIVERSAL DISPLAY CORP (US) 2023-04-26 EP disclosed
EP-3433246-B1 1-CYANO-PYRROLIDINE DERIVATIVES AS DBU INHIBITORS MISSION THERAPEUTICS LTD (GB) 2022-05-04 EP disclosed
EP-3780208-A1 FLOW BATTERY Panasonic Intellectual Property Management Co., Ltd. (JP) 2021-02-17 EP disclosed