Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | IDH1 | O75874 | 1/20 | 0.42 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.41 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6364918 | 0.83 | FFAR1 (0.55) | FFAR1FFAR4GLAHTR2BCNR1 | |
| SCHEMBL27718564 | 0.83 | GLA (0.49) | FFAR1FFAR4GLAHTR2BCNR1 | |
| SCHEMBL13756109 | 0.83 | GLA (0.47) | FFAR1FFAR4GLAHTR2BIDH1 | |
| SCHEMBL1554681 | 0.82 | ALDH1A1 (0.43) | LMNAMEN1KMT2A | |
| SCHEMBL19062339 | 0.81 | FFAR1 (0.49) | FFAR1FFAR4GLAHTR2BCNR1 | |
| SCHEMBL28865565 | 0.80 | HTR2B (0.50) | FFAR1FFAR4GLAHTR2BCNR1 | |
| SCHEMBL28248372 | 0.80 | HTR2B (0.54) | FFAR1FFAR4GLAHTR2BCNR1 | |
| SCHEMBL2154019 | 0.80 | GLA (0.53) | FFAR1FFAR4GLAHTR2BCNR1 | |
| SCHEMBL3109008 | 0.80 | FFAR1 (0.54) | FFAR1FFAR4GLAHTR2BCNR1 | |
| SCHEMBL7335965 | 0.79 | FFAR1 (0.57) | FFAR1FFAR4GLAHTR2BCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3778576-A1 | 2-CYANOPYRIMIDIN-4-YL CARBAMATE OR UREA DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION INCLUDING SAME | Hanlim Pharmaceutical Co., Ltd. (KR) | 2021-02-17 | — | — | EP | disclosed |