Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.68 |
| ▸ | USP2 | O75604 | 1/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | NAMPT | P43490 | 7/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21246579 | 0.89 | NAMPT (0.72) | ALDH1A1L3MBTL1USP2NPSR1TSHR | |
| SCHEMBL21227038 | 0.89 | NAMPT (0.62) | ALDH1A1NAMPTLMNAKCNJ1 | |
| SCHEMBL29437163 | 0.89 | NAMPT (0.62) | ALDH1A1NAMPTLMNAKCNJ1 | |
| SCHEMBL22729238 | 0.88 | NAMPT (0.65) | ALDH1A1L3MBTL1USP2NPSR1CYP1A2 | |
| SCHEMBL29437170 | 0.88 | NAMPT (0.65) | ALDH1A1L3MBTL1USP2NPSR1CYP1A2 | |
| SCHEMBL22729243 | 0.87 | NAMPT (0.72) | ALDH1A1L3MBTL1USP2NPSR1CYP1A2 | |
| SCHEMBL21246641 | 0.87 | ALDH1A1 (0.70) | ALDH1A1NAMPTLMNAKCNJ1 | |
| SCHEMBL29437164 | 0.87 | ALDH1A1 (0.70) | ALDH1A1NAMPTLMNAKCNJ1 | |
| SCHEMBL21246556 | 0.87 | NAMPT (0.59) | ALDH1A1L3MBTL1USP2NPSR1CYP1A2 | |
| SCHEMBL22729234 | 0.85 | LMNA (0.60) | ALDH1A1NAMPTLMNAKCNJ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11518744-B2 | Benzamide compound and preparation method, use, and pharmaceutical composition thereof | INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2022-12-06 | — | — | US | disclosed |
| US-20210047270-A1 | BENZAMIDE COMPOUND AND PREPARATION METHOD, USE, AND PHARMACEUTICAL COMPOSITION THEREOF | INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2021-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210047270-A1 | BENZAMIDE COMPOUND AND PREPARATION METHOD, USE, AND PHARMACEUTICAL COMPOSITION THEREOF | JAK2, STAT3, STAT5A | ALDH1A1 635/4885L3MBTL1 4608/4885USP2 2682/4885 |
| US-11518744-B2 | Benzamide compound and preparation method, use, and pharmaceutical composition thereof | JAK2, STAT3, STAT5A | ALDH1A1 635/4885L3MBTL1 4608/4885USP2 2682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.