Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.45 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | IGF1R | P08069 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14354395 | 0.77 | KDM4E (0.47) | KMOKDM4EALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL2302384 | 0.74 | SLC1A5 (0.38) | KMOEPHX2 | |
| SCHEMBL31361182 | 0.74 | SLC1A5 (0.38) | KMOEPHX2 | |
| SCHEMBL287491 | 0.74 | KMO (0.41) | KMOKDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL2301805 | 0.73 | DHODH (0.41) | KMOALDH1A1KMT2ADHODHAKR1C2 | |
| SCHEMBL2306249 | 0.73 | KMO (0.49) | KMOALPLKDM4EEPHX2RXRA | |
| SCHEMBL25379638 | 0.72 | SCN3A (0.44) | KMOALDH1A1KMT2AGAA | |
| Clopyralid SCHEMBL54779 | 0.72 | KMT2A (0.50) | KDM4EALDH1A1KMT2AL3MBTL1GAA | |
| Clopyralid SCHEMBL29371357 | 0.72 | KMT2A (0.50) | KDM4EALDH1A1KMT2AL3MBTL1GAA | |
| Clopyralid SCHEMBL8535196 | 0.72 | KMT2A (0.50) | KDM4EALDH1A1KMT2AL3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109956929-B | Heterocyclic derivative, preparation method, pharmaceutical composition and application thereof | 上海迪诺医药科技有限公司 | 2023-09-19 | — | — | CN | disclosed |
| WO-2023165957-A1 | SUBSTITUTED 1,2,4-THIADIAZOLYL PICOLINAMIDES, SALTS OR N-OXIDES THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | BAYER AKTIENGESELLSCHAFT (DE) | 2023-09-07 | — | — | WO | disclosed |
| EP-4238972-A1 | SUBSTITUTED 1,2,4-THIADIAZOLYL PICOLINAMIDES, SALTS OR N-OXIDES THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | Bayer AG (DE) | 2023-09-06 | — | — | EP | disclosed |
| CN-110156656-B | Five-membered heteroaromatic ring derivative, preparation method thereof, pharmaceutical composition and application | 上海迪诺医药科技有限公司 | 2023-04-07 | — | — | CN | disclosed |
| EP-2350008-B1 | METHOD FOR THE PREPARATION OF FUNCTIONALIZED TRIHALOMETHOXY SUBSTITUTED PYRIDINES | BAYER CROPSCIENCE AG (DE) | 2012-09-05 | — | — | EP | disclosed |
| EP-2350008-A1 | METHOD FOR THE PREPARATION OF FUNCTIONALIZED TRIHALOMETHOXY SUBSTITUTED PYRIDINES | Bayer CropScience AG (DE) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010040461-A1 | METHOD FOR THE PREPARATION OF FUNCTIONALIZED TRIHALOMETHOXY SUBSTITUTED PYRIDINES | BAYER CROPSCIENCE AG (DE) | 2010-04-15 | — | — | WO | disclosed |