⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10438113 | 0.98 | BLM (0.41) | — | |
| Hydrochloric Acid SCHEMBL17597680 | 0.98 | BLM (0.41) | — | |
| Trifluoroacetic Acid SCHEMBL17595021 | 0.89 | TSHR (0.33) | — | |
| SCHEMBL4242319 | 0.83 | — | — | |
| SCHEMBL1017726 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL30468940 | 0.78 | THRB (0.36) | — | |
| SCHEMBL22411680 | 0.78 | — | — | |
| SCHEMBL5660573 | 0.75 | HDAC2 (0.31) | — | |
| SCHEMBL3391017 | 0.75 | KDM5B (0.33) | — | |
| SCHEMBL4771907 | 0.73 | ALDH1A1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 220 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250388543-A1 | HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2025-12-25 | — | — | US | claimed |
| US-20250367229-A1 | Treatment of Immune-Related Disorders, Kidney Disorders, Liver Disorders, Hemolytic Disorders, and Oxidative Stress-Associated Disorders Using NRH, NARH and Reduced Derivatives Thereof | MITOPOWER LLC (US) | 2025-12-04 | — | — | US | claimed |
| WO-2025003367-A1 | VITAMIN COMPOSITION FOR USE IN COSMETIC FORMULATIONS | CLARIANT INTERNATIONAL LTD (CH) | 2025-01-02 | — | — | WO | claimed |
| US-20240382512-A1 | Treatment of Immune-Related Disorders, Kidney Disorders, Liver Disorders, Hemolytic Disorders, and Oxidative Stress-Associated Disorders Using NRH, NARH and Reduced Derivatives Thereof | MITOPOWER LLC | 2024-11-21 | — | — | US | claimed |
| EP-4313067-A1 | TREATMENT OF IMMUNE-RELATED DISORDERS, KIDNEY DISORDERS, LIVER DISORDERS, HEMOLYTIC DISORDERS, AND OXIDATIVE STRESS-ASSOCIATED DISORDERS USING NRH, NARH AND REDUCED DERIVATIVES THEREOF | Mitopower LLC (US) | 2024-02-07 | — | — | EP | claimed |
| US-20230014055-A1 | Treatment of Immune-Related Disorders, Kidney Disorders, Liver Disorders, Hemolytic Disorders, and Oxidative Stress-Associated Disorders Using NRH, NARH and Reduced Derivatives Thereof | MITOPOWER LLC | 2023-01-19 | — | — | US | claimed |
| WO-2022266322-A1 | TREATMENT OF IMMUNE-RELATED DISORDERS, KIDNEY DISORDERS, LIVER DISORDERS, HEMOLYTIC DISORDERS, AND OXIDATIVE STRESS-ASSOCIATED DISORDERS USING NRH, NARH AND REDUCED DERIVATIVES THEREOF | MITOPOWER LLC (US) | 2022-12-22 | — | — | WO | claimed |
| WO-2021098725-A1 | SYNTHETIC METHOD FOR NMN DERIVATIVE AND MEDICAL APPLICATIONS OF NMN AND ITS DERIVATIVE | TSINGHUA UNIVERSITY (CN) | 2021-05-27 | — | — | WO | claimed |
| CN-103889224-B | ANTIBACTERIAL COMPOUNDS AND METHODS FOR USE | PTC医疗公司 | 2017-05-24 | — | — | CN | claimed |
| CN-102115469-A | Preparation method for indoline-2-one derivative and application of same | UNIV ZHEJIANG | 2011-07-06 | — | — | CN | claimed |
| JP-5339263-A | — | — | None | — | — | JP | disclosed |
| JP-56061354-A | — | — | None | — | — | JP | disclosed |
| US-20250388541-A1 | HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2025-12-25 | — | — | US | disclosed |
| US-20250388543-A1 | HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2025-12-25 | — | — | US | disclosed |
| US-20250367229-A1 | Treatment of Immune-Related Disorders, Kidney Disorders, Liver Disorders, Hemolytic Disorders, and Oxidative Stress-Associated Disorders Using NRH, NARH and Reduced Derivatives Thereof | MITOPOWER LLC (US) | 2025-12-04 | — | — | US | disclosed |
| US-4645766-A | 1,2-dihydro-2-oxo-3-hydroxymethyl pyridines, compositions and use | THE UPJOHN COMPANY (US) | 1987-02-24 | — | — | US | disclosed |
| EP-0194750-A1 | Dihydropyridine alkanol amines, process for their preparation and pharmaceutical compositions containing them | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-09-17 | — | — | EP | disclosed |
| WO-1986004581-A1 | DIHYDROPYRIDINE ALKANOLAMINES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-08-14 | — | — | WO | disclosed |
| US-4288440-A | Pyridinones | THE UPJOHN COMPANY (US) | 1981-09-08 | — | — | US | disclosed |
| JP-S5661354-A | NICOTINIC ACID DERIVATIVE | MITSUBISHI CHEM IND LTD | 1981-05-26 | — | — | JP | disclosed |