Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 2/20 | 0.39 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.38 |
| ▸ | P2RY11 | Q96G91 | 2/20 | 0.38 |
| ▸ | HINT1 | P49773 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.35 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20056907 | 0.93 | NT5E (0.40) | NT5EP2RY1P2RY11HINT1ADORA2A | |
| SCHEMBL20056910 | 0.92 | NT5E (0.38) | NT5EP2RY1P2RY11HINT1ADORA2A | |
| SCHEMBL19827632 | 0.88 | CA5A (0.44) | NT5EP2RY1P2RY11ADORA1 | |
| SCHEMBL23010227 | 0.87 | NT5E (0.38) | NT5EP2RY1P2RY11ADORA2AADORA2B | |
| SCHEMBL18726343 | 0.87 | NT5E (0.39) | NT5EHINT1ADORA2AADORA2BADORA3 | |
| SCHEMBL16024938 | 0.84 | P2RY1 (0.48) | P2RY1P2RY11 | |
| SCHEMBL19187036 | 0.84 | NT5E (0.41) | NT5EP2RY1P2RY11SLC29A1 | |
| SCHEMBL23584291 | 0.84 | ADORA2A (0.45) | ADORA2AADORA2BADORA3ADORA1SLC29A1 | |
| SCHEMBL10266182 | 0.84 | ADORA2A (0.45) | ADORA2AADORA2BADORA3ADORA1SLC29A1 | |
| SCHEMBL13469562 | 0.84 | ADORA2A (0.45) | ADORA2AADORA2BADORA3ADORA1SLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2935303-B1 | 4'-FLUORO-NUCLEOSIDES, 4'-FLUORO-NUCLEOTIDES AND ANALOGS THEREOF FOR THE TREATMENT OF HCV | JANSSEN BIOPHARMA INC (US) | 2021-02-17 | — | — | EP | disclosed |