Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | NT5E | P21589 | 2/20 | 0.44 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.42 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.42 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.42 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | FBP1 | P09467 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.42 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.42 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16024938 | 0.92 | P2RY1 (0.48) | P2RY1P2RY11P2RX3RNASEL | |
| SCHEMBL19187036 | 0.90 | NT5E (0.41) | NT5EP2RY1SRCP2RY2P2RY11 | |
| SCHEMBL18726343 | 0.89 | NT5E (0.39) | CA5ANT5EADORA1 | |
| SCHEMBL23010941 | 0.88 | NT5E (0.39) | NT5EP2RY1ADORA1P2RY11 | |
| SCHEMBL19186857 | 0.88 | FUT5 (0.40) | NT5EP2RY1P2RY11P2RX3RNASEL | |
| SCHEMBL20056910 | 0.88 | NT5E (0.38) | NT5EP2RY1ADORA1P2RY11 | |
| SCHEMBL19827691 | 0.87 | HINT1 (0.41) | NT5EADORA1 | |
| SCHEMBL23584291 | 0.86 | ADORA2A (0.45) | ADORA1 | |
| SCHEMBL10266182 | 0.86 | ADORA2A (0.45) | ADORA1 | |
| SCHEMBL13469562 | 0.86 | ADORA2A (0.45) | ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2852605-B1 | 3',5'-CYCLIC PHOSPHATE PRODRUGS FOR HCV INFECTION | IDENIX PHARMACEUTICALS LLC (US) | 2018-01-31 | — | — | EP | disclosed |