Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23011118 | 0.94 | SMN1; SMN2 (0.42) | NPC1RAB9ASMN1; SMN2CYP2C19TSHR | |
| SCHEMBL22992372 | 0.85 | OPRM1 (0.47) | CYP2C19TSHRLMNAOPRM1ALDH1A1 | |
| SCHEMBL16423615 | 0.83 | LMNA (0.58) | SMN1; SMN2CYP2C19TSHRMEN1CYP1A2 | |
| SCHEMBL4859733 | 0.78 | LMNA (0.46) | RAB9ASMN1; SMN2CYP2C19TSHRMEN1 | |
| SCHEMBL22992467 | 0.78 | OPRM1 (0.52) | CYP2C19TSHRLMNAOPRM1CYP2C9 | |
| SCHEMBL22992487 | 0.78 | OPRM1 (0.43) | OPRM1ALDH1A1ALOX5 | |
| SCHEMBL23011158 | 0.77 | LMNA (0.53) | SMN1; SMN2CYP2C19TSHRMEN1CYP1A2 | |
| SCHEMBL23005733 | 0.74 | OPRM1 (0.40) | CYP2C19OPRM1CYP2C9ALDH1A1ALOX5 | |
| SCHEMBL1769341 | 0.74 | LMNA (0.64) | SMN1; SMN2CYP2C19TSHRMEN1CYP1A2 | |
| SCHEMBL20703536 | 0.74 | MEN1 (0.47) | SMN1; SMN2CYP2C19TSHRMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021027722-A1 | IMMUNOMODULATOR | 成都先导药物开发股份有限公司 | 2021-02-18 | — | — | WO | disclosed |