Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13853860 | 0.81 | KMT2A (0.47) | MAPK1MEN1FAAHKMT2AEPHX2 | |
| SCHEMBL22916892 | 0.81 | KMT2A (0.47) | MAPK1MEN1FAAHKMT2AKDM4E | |
| SCHEMBL12643180 | 0.80 | MEN1 (0.43) | MAPK1MEN1FAAHKMT2AKDM4E | |
| SCHEMBL20458026 | 0.80 | MEN1 (0.47) | MAPK1MEN1FAAHKMT2AKDM4E | |
| SCHEMBL5909062 | 0.78 | MEN1 (0.62) | MAPK1MEN1FAAHKMT2AKDM4E | |
| SCHEMBL10076774 | 0.77 | MAPK1 (0.42) | MAPK1MEN1FAAHKMT2AKDM4E | |
| SCHEMBL12138292 | 0.77 | MEN1 (0.52) | MAPK1MEN1FAAHKMT2AKDM4E | |
| SCHEMBL11923590 | 0.77 | MEN1 (0.52) | MAPK1MEN1FAAHKMT2AKDM4E | |
| SCHEMBL12448069 | 0.77 | EPHX1 (0.63) | MAPK1KDM4EHIF1AEPHX2TSHR | |
| SCHEMBL20938365 | 0.76 | MEN1 (0.43) | MAPK1MEN1FAAHKMT2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4289857-A1 | DRUG CONJUGATE OF GLUCOCORTICOID RECEPTOR AGONIST, AND APPLICATION THEREOF IN MEDICINE | Shanghai Senhui Medicine Co., Ltd. (CN) | 2023-12-13 | — | — | EP | disclosed |
| EP-3778573-A1 | COMPOUND WITH ANTICANCER ACTIVITY | Kyowa Kirin Co., Ltd. (JP) | 2021-02-17 | — | — | EP | disclosed |