Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25637025 | 0.87 | MEN1 (0.45) | MEN1KMT2AMAPK1MTNR1AMTNR1B | |
| SCHEMBL26249106 | 0.85 | MEN1 (0.46) | MEN1KMT2AMAPK1FAAHALDH1A1 | |
| SCHEMBL19901903 | 0.85 | KMT2A (0.54) | MEN1KMT2AMAPK1FAAHALDH1A1 | |
| SCHEMBL861319 | 0.85 | KMT2A (0.54) | MEN1KMT2AMAPK1FAAHALDH1A1 | |
| SCHEMBL25532300 | 0.83 | KMT2A (0.51) | MEN1KMT2AMAPK1FAAHALDH1A1 | |
| SCHEMBL19101863 | 0.83 | KDM4E (0.43) | MEN1KMT2AMAPK1FAAHALDH1A1 | |
| SCHEMBL17130496 | 0.83 | MEN1 (0.42) | MEN1KMT2AMAPK1FAAHALDH1A1 | |
| SCHEMBL26707067 | 0.83 | MEN1 (0.44) | MEN1KMT2AMAPK1FAAHALDH1A1 | |
| SCHEMBL21129775 | 0.82 | ACHE (0.41) | MEN1KMT2AMAPK1FAAHALDH1A1 | |
| SCHEMBL22856965 | 0.82 | MEN1 (0.46) | MEN1KMT2AMAPK1MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10039816-B2 | Siderophore-based immunization against gram-negative bacteria | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10039816-B2 | Siderophore-based immunization against gram-negative bacteria | SLC40A1, SFXN1, SLC75A1 | MEN1 2216/4885KMT2A 4049/4885MAPK1 4334/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.