Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.43 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.43 |
| ▸ | ITGAL | P20701 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GGT1 | P19440 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | MMP9 | P14780 | 2/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | ECE1 | P42892 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenol SCHEMBL170523 | 0.91 | ALDH1A1 (0.39) | ALDH1A1RAB9AKMT2AMEN1ITGB2 | |
| Phenol SCHEMBL29254468 | 0.91 | ALDH1A1 (0.39) | ALDH1A1RAB9AKMT2AMEN1ITGB2 | |
| SCHEMBL1226550 | 0.85 | ECE1 (0.41) | ALDH1A1RAB9AKMT2AMEN1ITGB2 | |
| SCHEMBL1226547 | 0.85 | ECE1 (0.41) | ALDH1A1RAB9AKMT2AMEN1ITGB2 | |
| Phenol SCHEMBL27348628 | 0.83 | ALDH1A1 (0.46) | ALDH1A1RAB9AKMT2AMEN1ITGB2 | |
| Phenol SCHEMBL28342610 | 0.83 | ALDH1A1 (0.46) | ALDH1A1RAB9AKMT2AMEN1ITGB2 | |
| Phenol SCHEMBL29187478 | 0.82 | ALDH1A1 (0.38) | ALDH1A1KDM4EMAPTCA2CA1 | |
| Phenol SCHEMBL29011359 | 0.81 | ALDH1A1 (0.49) | ALDH1A1RAB9AKMT2AMEN1ITGB2 | |
| SCHEMBL3451052 | 0.78 | ALDH1A1 (0.54) | ALDH1A1RAB9AKMT2AMEN1ITGB2 | |
| SCHEMBL3451049 | 0.78 | ALDH1A1 (0.54) | ALDH1A1RAB9AKMT2AMEN1ITGB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118267479-A | Combination therapy using chemokine receptor 2 (CCR 2) antagonists and PD-1/PD-L1 inhibitors | 凯莫森特里克斯股份有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-113307772-B | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2024-06-28 | — | — | CN | disclosed |
| CN-114502531-B | Process for preparing plasma kallikrein inhibitors | 雷佐鲁特公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-118019735-A | Arylsulfonyl compounds as CCR6 inhibitors | 坎莫森特里克斯公司 | 2024-05-10 | — | — | CN | disclosed |
| CN-117813086-A | Arylsulfonyl (hydroxy) piperidines as CCR6 inhibitors | 坎莫森特里克斯公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-117794525-A | Anticancer compounds | 加利福尼亚大学董事会 | 2024-03-29 | — | — | CN | disclosed |
| CN-117529315-A | Imidazole-containing ALK2 kinase inhibitors | 生物水晶制药公司 | 2024-02-06 | — | — | CN | disclosed |
| CN-117164499-A | Substituted benzofurans, benzopyrroles, benzothiophenes and structurally related complement inhibitors | 拜奥克里斯特制药公司 | 2023-12-05 | — | — | CN | disclosed |
| CN-111712242-B | Combination therapy using chemokine receptor 2 (CCR 2) antagonists and PD-1/PD-L1 inhibitors | 凯莫森特里克斯股份有限公司 | 2023-11-24 | — | — | CN | disclosed |
| CN-117120419-A | KLK5 bicyclic heteroaromatic inhibitors | 拜奥克里斯特制药公司 | 2023-11-24 | — | — | CN | disclosed |
| CN-102574789-A | Pyrrolidinone carboxamide derivatives as chemokine-R (CHEMR23) modulators | CHEMOCENTRYX INC | 2012-07-11 | — | — | CN | disclosed |
| CN-102459253-A | Azole substituted indazole compounds as PI 3-kinase inhibitors | GLAXO GROUP LTD | 2012-05-16 | — | — | CN | disclosed |
| CN-102459221-A | Thiophene derivatives | SUMITOMO CHEMICAL CO | 2012-05-16 | — | — | CN | disclosed |
| CN-102417487-A | Indazole, benzisoxazole and benzisothiazole kinase inhibitors | ABBOTT LAB | 2012-04-18 | — | — | CN | disclosed |
| CN-102378762-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2012-03-14 | — | — | CN | disclosed |
| CN-102356081-A | Bicyclic compounds for the reduction of beta-amyloid production | BRISTOL MYERS SQUIBB CO | 2012-02-15 | — | — | CN | disclosed |
| CN-102336702-A | Pharmaceutical salts and polymorphs of a factor XA inhibitor n-(5-chloro-pyridin-2-yl)-2-(4-cyano-benzoyl-amino)-5-methoxy-benzamide hydrochloride | MILLENNIUM PHARM INC | 2012-02-01 | — | — | CN | disclosed |
| CN-102153539-A | 3-aminopyrrolidine derivatives as modulators of chemokine receptors | INCYTE CORP | 2011-08-17 | — | — | CN | disclosed |
| CN-1481377-A | Cyclic beta-amino acid derivatives as inhibitors of matrix metalloproteinases and TNF-alpha | ����˹�ж�-����˹˹����ҩƷ��˾ | 2004-03-10 | — | — | CN | disclosed |
| CN-1439008-A | 1-(heteroaryl-henyl)-condensed pyrazol derivatives as factor XA inhibitors | BRISTOL MYERS SQUIBB CO (US) | 2003-08-27 | — | — | CN | disclosed |