Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 5/20 | 0.38 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.38 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.38 |
| ▸ | ITGAL | P20701 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenol SCHEMBL29254468 | 1.00 | ALDH1A1 (0.39) | ALDH1A1RAB9AMEN1KMT2ALMNA | |
| Phenol SCHEMBL23011978 | 0.91 | ALDH1A1 (0.45) | ALDH1A1RAB9AMEN1KMT2ALMNA | |
| Phenol SCHEMBL29187478 | 0.91 | ALDH1A1 (0.38) | ALDH1A1LMNAHSD17B10HPGDSKDM4E | |
| SCHEMBL3441239 | 0.83 | ECE1 (0.38) | ALDH1A1MEN1KMT2AITGB2ICAM1 | |
| SCHEMBL1221420 | 0.83 | ECE1 (0.38) | ALDH1A1MEN1KMT2AITGB2ICAM1 | |
| Phenol SCHEMBL1847412 | 0.83 | ALDH1A1 (0.40) | ALDH1A1RAB9AMEN1KMT2AHPGDS | |
| Phenol SCHEMBL28162156 | 0.83 | ALDH1A1 (0.40) | ALDH1A1RAB9AMEN1KMT2AHPGDS | |
| Phenol SCHEMBL2640784 | 0.83 | ALDH1A1 (0.40) | ALDH1A1RAB9AMEN1KMT2AHPGDS | |
| SCHEMBL28483122 | 0.77 | KDM4E (0.42) | ALDH1A1RAB9AMEN1KMT2ALMNA | |
| SCHEMBL30731126 | 0.77 | KDM4E (0.42) | ALDH1A1RAB9AMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2091 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1227813-B1 | REVERSE-TURN MIMETICS AS alpha 4ß INTEGRIN INHIBITORS | MYRIAD GENETICS INC (US) | 2007-08-22 | — | — | EP | claimed |
| US-6514978-B2 | Compounds such as 1-(n-(2-(amidinoaminooxy)ethyl)amino) carbonylmethyl-6-methyl-3-(phenethylamino)-pyrazinone attached to a polymer coated onto a medical device for blood collection or storage; antiagglomerants | 3-DIMENSIONAL PHARMACEUTICALS, INC. | 2003-02-04 | — | — | US | claimed |
| US-20010021713-A1 | Thromboresistant materials incorporating pyrazinone protease inhibitors | LU TIANBAO (US) | 2001-09-13 | — | — | US | claimed |
| US-RE50050-E1 | Pyrimidinedione compounds | MyoKardia, Inc. (US) | 2024-07-23 | — | — | US | disclosed |
| US-12043610-B2 | Substituted benzofuran, benzopyrrole, benzothiophene, and structurally related complement inhibitors | BIOCRYST PHARMACEUTICALS, INC. (US) | 2024-07-23 | — | — | US | disclosed |
| US-20240238271-A1 | PHARMACEUTICAL COMPOSITION FOR ENHANCING CELL KILLING, AND USE THEREOF | SHANGHAI JUNCELL THERAPEUTICS CO., LTD. (CN) | 2024-07-18 | — | — | US | disclosed |
| US-20240239752-A1 | BICYCLIC HETEROAROMATIC INHIBITORS OF KLK5 | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2024-07-18 | — | — | US | disclosed |
| EP-3873904-B1 | TETRAHYDROPYRAN (THP)-SUBSTITUTED BICYCLIC-PYRIMIDINEDIONE COMPOUNDS | MYOKARDIA INC (US) | 2024-07-10 | — | — | EP | disclosed |
| WO-2024145422-A1 | SYNTHESIS OF 2-PHENYL-2-AMINO-CYCLOHEXAN-1-ONE DERIVATIVES | GILGAMESH PHARMACEUTICALS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |
| EP-4387609-A2 | ARYL SULFONYL (HYDROXY) PIPERIDINES AS CCR6 INHIBITORS | ChemoCentryx, Inc. (US) | 2024-06-26 | — | — | EP | disclosed |
| EP-4387965-A2 | ARYL SULFONYL COMPOUNDS AS CCR6 INHIBITORS | ChemoCentryx, Inc. (US) | 2024-06-26 | — | — | EP | disclosed |
| EP-0508699-A1 | 9-Deoxo-8a-aza-8a-homoerythromycin a derivatives modified at the 4\"- and 8a-positions | MERCK & CO. INC. (US) | 1992-10-14 | — | — | EP | disclosed |
| EP-0508795-A1 | 8a-aza-8a-homoerythromycin cyclic iminoethers | MERCK & CO. INC. (US) | 1992-10-14 | — | — | EP | disclosed |
| EP-0508725-A1 | Novel process for the preparation of 8a-aza-8a-homoerythromycin cyclic iminoethers | MERCK & CO. INC. (US) | 1992-10-14 | — | — | EP | disclosed |
| EP-0507595-A1 | 8A-aza-8A-homoerythromycin lactams | MERCK & CO. INC. (US) | 1992-10-07 | — | — | EP | disclosed |
| EP-0503932-A1 | 9-Deoxo-9(z)-hydroxy-iminoerythromycin A and O-derivatives thereof | MERCK & CO. INC. (US) | 1992-09-16 | — | — | EP | disclosed |
| EP-0503949-A1 | Novel process for the preparation of 9-deoxo-9(z)-hydroxyiminoerythromycin A | MERCK & CO. INC. (US) | 1992-09-16 | — | — | EP | disclosed |
| EP-0486280-A2 | Piperidinylcamphorsulfonyl oxytocin antagonists | MERCK & CO. INC. (US) | 1992-05-20 | — | — | EP | disclosed |
| WO-1992007821-A1 | DIASTEREOISOMERS OF BICYCLO-SUBSTITUTED PHENYLACETONITRILE DERIVATIVES | G.D. SEARLE & CO. (US) | 1992-05-14 | — | — | WO | disclosed |
| EP-0478363-A2 | Novel sulfonamide fibrinogen receptor antagonists | MERCK & CO. INC. (US) | 1992-04-01 | — | — | EP | disclosed |