Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 8/20 | 0.67 |
| ▸ | FBP1 | P09467 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Praxadine SCHEMBL94070 | 0.82 | — | — | |
| Praxadine SCHEMBL28203296 | 0.80 | — | — | |
| Praxadine SCHEMBL3086435 | 0.80 | — | — | |
| Praxadine SCHEMBL52095 | 0.80 | — | — | |
| Praxadine SCHEMBL5396070 | 0.77 | NOS1 (0.74) | NOS1FBP1 | |
| Praxadine SCHEMBL31705643 | 0.69 | — | — | |
| Trifluoromethanesulfonic Acid SCHEMBL2670016 | 0.69 | CA1 (0.42) | — | |
| SCHEMBL14385213 | 0.65 | — | — | |
| Trifluoromethanesulfonic Acid SCHEMBL18641287 | 0.65 | F2 (0.39) | — | |
| SCHEMBL19065759 | 0.65 | NOS1 (0.44) | NOS1FBP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2342181-A1 | NOVEL UREA AND THIOUREA DERIVATIVES | Topo Target A/S (DK) | 2011-07-13 | — | — | EP | disclosed |
| WO-2010023307-A1 | NOVEL UREA AND THIOUREA DERIVATIVES | TOPOTARGET A/S (DK) | 2010-03-04 | — | — | WO | disclosed |