Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.54 |
| ▸ | RELA | Q04206 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | UTRN | P46939 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29479847 | 1.00 | HSD17B10 (0.54) | HSD17B10ALDH1A1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL1024034 | 0.82 | HSD17B10 (0.78) | HSD17B10ALDH1A1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL28701725 | 0.80 | HDAC6 (0.54) | HSD17B10ALDH1A1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL29479691 | 0.80 | HDAC6 (0.54) | HSD17B10ALDH1A1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL5226589 | 0.80 | NPC1 (0.68) | HSD17B10ALDH1A1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL29479584 | 0.80 | PIK3CB (0.67) | HSD17B10SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL23033952 | 0.80 | PIK3CB (0.67) | HSD17B10SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL28935979 | 0.79 | MAPT (0.58) | HSD17B10ALDH1A1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL28559369 | 0.77 | SMN1; SMN2 (0.66) | HSD17B10ALDH1A1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL23012808 | 0.77 | ACSL1 (0.46) | HSD17B10SMN1; SMN2NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269725-A | Anti-influenza virus compound and preparation method and application thereof | 四川海思科制药有限公司 | 2022-04-01 | — | — | CN | disclosed |
| WO-2021032209-A1 | ANTI-INFLUENZA VIRUS COMPOUND, PREPARATION METHOD AND USE THEREOF | 四川海思科制药有限公司 | 2021-02-25 | — | — | WO | disclosed |