Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 13/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CEPT1 | Q9Y6K0 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29479691 | 1.00 | HDAC6 (0.54) | HDAC6MAPTKDM4EPOLBTHRB | |
| SCHEMBL23012299 | 0.86 | RAB9A (0.69) | MAPTKDM4EPOLBTP53SMN1; SMN2 | |
| SCHEMBL28698102 | 0.86 | MAPT (0.50) | HDAC6MAPTKDM4EPOLBTP53 | |
| SCHEMBL23033654 | 0.84 | MAPT (0.54) | MAPTKDM4EPOLBTHRBTP53 | |
| SCHEMBL23034143 | 0.83 | MAPT (0.71) | MAPTKDM4EPOLBTHRBTP53 | |
| SCHEMBL23033954 | 0.82 | ACSL1 (0.48) | HDAC6MAPTKDM4EPOLBTHRB | |
| SCHEMBL28698129 | 0.82 | ACSL1 (0.48) | HDAC6MAPTKDM4EPOLBTHRB | |
| SCHEMBL29479781 | 0.81 | MAPT (0.46) | HDAC6MAPTKDM4EPOLBTHRB | |
| SCHEMBL23012747 | 0.81 | MAPT (0.46) | HDAC6MAPTKDM4EPOLBTHRB | |
| SCHEMBL28695332 | 0.81 | KMT2A (0.48) | HDAC6MAPTKDM4EPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269725-A | Anti-influenza virus compound and preparation method and application thereof | 四川海思科制药有限公司 | 2022-04-01 | — | — | CN | disclosed |