Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.60 |
| ▸ | NPC1 | O15118 | 9/20 | 0.59 |
| ▸ | RAB9A | P51151 | 9/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.59 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.59 |
| ▸ | RELA | Q04206 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 4/20 | 0.54 |
| ▸ | AGPAT2 | O15120 | 2/20 | 0.51 |
| ▸ | UTRN | P46939 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | NCOA2 | Q15596 | 2/20 | 0.48 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23033512 | 0.90 | NPC1 (0.61) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL28936032 | 0.88 | AGPAT2 (0.47) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL28710759 | 0.83 | RAB9A (0.56) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL23012577 | 0.80 | NPC1 (0.61) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL23034143 | 0.79 | MAPT (0.71) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL23033336 | 0.78 | MAPT (0.69) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL23012154 | 0.76 | HDAC6 (0.46) | MAPTRAB9ASMN1; SMN2TP53POLB | |
| SCHEMBL28713901 | 0.76 | MAPT (0.37) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL23012208 | 0.76 | MAPT (0.60) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL23012293 | 0.75 | NPC1 (0.46) | MAPTNPC1RAB9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021032209-A1 | ANTI-INFLUENZA VIRUS COMPOUND, PREPARATION METHOD AND USE THEREOF | 四川海思科制药有限公司 | 2021-02-25 | — | — | WO | disclosed |
| WO-2021032209-A1 | ANTI-INFLUENZA VIRUS COMPOUND, PREPARATION METHOD AND USE THEREOF | 四川海思科制药有限公司 | 2021-02-25 | — | — | WO | disclosed |