Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.69 |
| ▸ | NPC1 | O15118 | 7/20 | 0.57 |
| ▸ | RAB9A | P51151 | 7/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.53 |
| ▸ | RELA | Q04206 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | UTRN | P46939 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 3/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.50 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.50 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23033340 | 0.87 | MAPT (0.53) | MAPTRAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL23542084 | 0.83 | MAPT (0.78) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL23033337 | 0.83 | RAB9A (0.67) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL23034143 | 0.81 | MAPT (0.71) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL23012571 | 0.78 | MAPT (0.60) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL2244809 | 0.75 | NPC1 (0.85) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL23012175 | 0.74 | NPC1 (0.70) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL23034137 | 0.74 | NPC1 (0.67) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL29479597 | 0.74 | NPC1 (0.70) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL4082942 | 0.74 | ALDH1A1 (0.79) | MAPTNPC1RAB9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021032209-A1 | ANTI-INFLUENZA VIRUS COMPOUND, PREPARATION METHOD AND USE THEREOF | 四川海思科制药有限公司 | 2021-02-25 | — | — | WO | disclosed |