SCHEMBL23012803

SCHEMBL23012803

CC(=O)Nc1ccc2nn(-c3ccnc(C(=O)O)c3)cc2c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.41
NPC1 O15118 5/20 0.41
RAB9A P51151 4/20 0.41
MAPT P10636 3/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
PABPC1 P11940 1/20 0.41
LDHA P00338 2/20 0.41
GLA P06280 1/20 0.40
TNNI3 P19429 1/20 0.40
TNNT2 P45379 1/20 0.40
TNNC1 P63316 1/20 0.40
RUNX1 Q01196 1/20 0.40
CBFB Q13951 1/20 0.40
PTGES O14684 1/20 0.40
ALDH1A1 P00352 3/20 0.39
HPGD P15428 2/20 0.39
GAA P10253 1/20 0.39
KDM5A P29375 1/20 0.39
KDM4D Q6B0I6 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29479623 1.00 KDM4E (0.41) KDM4ENPC1RAB9AMAPTMEN1
SCHEMBL29479815 0.89 KDM4E (0.40) KDM4ENPC1RAB9AMAPTMEN1
SCHEMBL28707263 0.89 KDM4E (0.40) KDM4ENPC1RAB9AMAPTMEN1
SCHEMBL24572943 0.78 ESR2 (0.44) KDM4ENPC1RAB9AMAPTMEN1
SCHEMBL29479808 0.76 ACSS2 (0.40) PTGESADORA3NOTUM
SCHEMBL23012622 0.76 ACSS2 (0.40) PTGESADORA3NOTUM
SCHEMBL5906610 0.74 KDM4E (0.52) KDM4ENPC1RAB9AMAPTMEN1
SCHEMBL23033519 0.74 NR2E1 (0.39) KDM4ENPC1RAB9AMAPTMEN1
SCHEMBL17778532 0.72 KDM4E (0.67) KDM4ENPC1RAB9AMAPTMEN1
SCHEMBL30297439 0.72 PTGES (0.43) PTGESADORA3NOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114269725-A Anti-influenza virus compound and preparation method and application thereof 四川海思科制药有限公司 2022-04-01 CN disclosed
WO-2021032209-A1 ANTI-INFLUENZA VIRUS COMPOUND, PREPARATION METHOD AND USE THEREOF 四川海思科制药有限公司 2021-02-25 WO disclosed