Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.45 |
| ▸ | FNTB | P49356 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23028550 | 0.83 | CKS1B (0.47) | FNTAFNTBDRD2KDM4EJAK2 | |
| SCHEMBL27910666 | 0.82 | SCN9A (0.47) | FNTAFNTBDRD2SCN9AKDM1A | |
| SCHEMBL23028551 | 0.76 | KCNH2 (0.45) | DRD2SCN9AJAK2JAK1JAK3 | |
| SCHEMBL27030452 | 0.76 | SMN1; SMN2 (0.45) | FNTAFNTBDRD2KDM4ESMN1; SMN2 | |
| SCHEMBL23013704 | 0.74 | CYP3A4 (0.48) | SMN1; SMN2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL2779242 | 0.74 | FNTA (0.41) | FNTAFNTBDRD2HTR2AHRH1 | |
| SCHEMBL2779240 | 0.74 | FNTA (0.41) | FNTAFNTBDRD2HTR2AHRH1 | |
| SCHEMBL210366 | 0.74 | OPRD1 (0.42) | FNTAFNTBDRD2KDM4ESCN9A | |
| SCHEMBL21571608 | 0.73 | CACNA1I (0.43) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL14375269 | 0.73 | ALDH1A1 (0.49) | DRD2SCN9AACHEJAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4017849-A1 | ENZYME INHIBITORS | Kalvista Pharmaceuticals Limited (GB) | 2022-06-29 | — | — | EP | disclosed |
| WO-2021032934-A1 | ENZYME INHIBITORS | KALVISTA PHARMACEUTICALS LIMITED (GB) | 2021-02-25 | — | — | WO | disclosed |