Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 13/20 | 0.43 |
| ▸ | CCKAR | P32238 | 10/20 | 0.43 |
| ▸ | NOTCH1 | P46531 | 5/20 | 0.42 |
| ▸ | RBPJ | Q06330 | 3/20 | 0.42 |
| ▸ | NOTCH3 | Q9UM47 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29692162 | 1.00 | CCKBR (0.43) | CCKBRCCKARNOTCH1RBPJNOTCH3 | |
| SCHEMBL29939406 | 0.93 | CCKBR (0.46) | CCKBRCCKARNOTCH1RBPJNOTCH3 | |
| SCHEMBL29692200 | 0.93 | CCKBR (0.45) | CCKBRCCKARNOTCH1RBPJ | |
| SCHEMBL23013106 | 0.93 | CCKBR (0.45) | CCKBRCCKARNOTCH1RBPJ | |
| SCHEMBL28749206 | 0.91 | NOTCH1 (0.41) | CCKBRCCKARNOTCH1RBPJNOTCH3 | |
| SCHEMBL29692163 | 0.91 | NOTCH1 (0.41) | CCKBRCCKARNOTCH1RBPJNOTCH3 | |
| SCHEMBL23013301 | 0.91 | CCKBR (0.52) | CCKBRCCKAR | |
| SCHEMBL29692231 | 0.91 | CCKBR (0.52) | CCKBRCCKAR | |
| SCHEMBL29939424 | 0.91 | CCKBR (0.45) | CCKBRCCKARNOTCH1RBPJ | |
| SCHEMBL23013257 | 0.91 | CCKBR (0.45) | CCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114555604-A | Pharmaceutical compounds | 瑞威有限公司 | 2022-05-27 | — | — | CN | claimed |
| EP-4017856-A1 | PHARMACEUTICAL COMPOUNDS | Reviral Limited (GB) | 2022-06-29 | — | — | EP | disclosed |
| WO-2021032992-A1 | PHARMACEUTICAL COMPOUNDS | ReViral Limited (GB) | 2021-02-25 | — | — | WO | disclosed |