Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTCH1 | P46531 | 4/20 | 0.41 |
| ▸ | RBPJ | Q06330 | 3/20 | 0.41 |
| ▸ | CCKBR | P32239 | 14/20 | 0.40 |
| ▸ | CCKAR | P32238 | 11/20 | 0.40 |
| ▸ | NOTCH3 | Q9UM47 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28749206 | 1.00 | NOTCH1 (0.41) | NOTCH1RBPJCCKBRCCKARNOTCH3 | |
| SCHEMBL23013160 | 0.93 | CCKBR (0.43) | CCKBRCCKAR | |
| SCHEMBL29692162 | 0.91 | CCKBR (0.43) | NOTCH1RBPJCCKBRCCKARNOTCH3 | |
| SCHEMBL23013233 | 0.91 | CCKBR (0.43) | NOTCH1RBPJCCKBRCCKARNOTCH3 | |
| SCHEMBL23013105 | 0.90 | CCKBR (0.41) | NOTCH1RBPJCCKBRCCKARNOTCH3 | |
| SCHEMBL29692249 | 0.90 | CCKBR (0.41) | NOTCH1RBPJCCKBRCCKARNOTCH3 | |
| SCHEMBL23013106 | 0.90 | CCKBR (0.45) | NOTCH1RBPJCCKBRCCKAR | |
| SCHEMBL29692200 | 0.90 | CCKBR (0.45) | NOTCH1RBPJCCKBRCCKAR | |
| SCHEMBL23013247 | 0.89 | CCKBR (0.46) | NOTCH1RBPJCCKBRCCKAR | |
| SCHEMBL29692236 | 0.89 | CCKBR (0.46) | NOTCH1RBPJCCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114555604-B | Pharmaceutical compounds | 辉瑞公司 | 2024-11-15 | — | — | CN | claimed |
| EP-4017856-A1 | PHARMACEUTICAL COMPOUNDS | Reviral Limited (GB) | 2022-06-29 | — | — | EP | claimed |
| US-11634425-B2 | Pharmaceutical compounds | PFIZER INC. (US) | 2023-04-25 | — | — | US | disclosed |
| EP-4017856-A1 | PHARMACEUTICAL COMPOUNDS | Reviral Limited (GB) | 2022-06-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11634425-B2 | Pharmaceutical compounds | GABRA6, CHRNA6, CNR1 | NOTCH1 4652/4885RBPJ 1150/4885CCKBR 257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.