SCHEMBL23014195

SCHEMBL23014195

CCS(=O)(=O)c1cc(-c2ccc3c(c2)OC(F)(F)O3)cnc1-n1ncc2cc(C(F)(F)F)cnc2c1=O

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
RORC P51449 1/20 0.32
KIF11 P52732 1/20 0.32
GPR55 Q9Y2T6 1/20 0.31
DDR1 Q08345 2/20 0.31
KMT2A Q03164 1/20 0.30
CTSD P07339 1/20 0.30
BACE1 P56817 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23013263 0.85 DDR1 (0.39) GPR55DDR1
SCHEMBL23013624 0.84 GRIN2B (0.41)
SCHEMBL23013731 0.84 ALDH1A1 (0.37) DDR1KMT2A
SCHEMBL23013658 0.83 KIF11 (0.37) KIF11DDR1
SCHEMBL23013988 0.83 GRIN2B (0.39) DDR1
SCHEMBL23014161 0.82 DDR1 (0.35) DDR1KMT2A
SCHEMBL23013669 0.82 DDR1 (0.35) DDR1
SCHEMBL23013871 0.81 DDR1 (0.36) DDR1KMT2A
SCHEMBL23013314 0.80 DDR1 (0.33) DDR1KMT2A
SCHEMBL23013892 0.76 TRPV1 (0.40) DDR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021033141-A1 FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS PEST CONTROL AGENTS PI INDUSTRIES LTD. (IN) 2021-02-25 WO disclosed