Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.40 |
| ▸ | ACE | P12821 | 6/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.38 |
| ▸ | TLR2 | O60603 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | MDM4 | O15151 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23014548 | 1.00 | PRCP (0.42) | PRCPMDM2ACEACE2TLR2 | |
| SCHEMBL24817625 | 0.88 | PRCP (0.37) | PRCPMDM2ACETLR2PTPN1 | |
| SCHEMBL29757443 | 0.88 | PRCP (0.37) | PRCPMDM2ACETLR2PTPN1 | |
| SCHEMBL24817624 | 0.88 | PRCP (0.37) | PRCPMDM2ACETLR2PTPN1 | |
| SCHEMBL23030719 | 0.88 | PRCP (0.37) | PRCPMDM2ACETLR2PTPN1 | |
| SCHEMBL23014552 | 0.87 | MDM2 (0.48) | MDM2TLR2PTPN1MDM4TP53 | |
| SCHEMBL29757411 | 0.87 | MDM2 (0.48) | MDM2TLR2PTPN1MDM4TP53 | |
| SCHEMBL23014551 | 0.87 | MDM2 (0.48) | MDM2TLR2PTPN1MDM4TP53 | |
| SCHEMBL30962356 | 0.86 | PRCP (0.46) | PRCPMDM2ACEACE2MDM4 | |
| SCHEMBL23014547 | 0.83 | ACE (0.35) | ACEACE2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4017866-A1 | METHODS OF MAKING INCRETIN ANALOGS | Eli Lilly and Company (US) | 2022-06-29 | — | — | EP | disclosed |
| WO-2021034815-A1 | METHODS OF MAKING INCRETIN ANALOGS | ELI LILLY AND COMPANY (US) | 2021-02-25 | — | — | WO | disclosed |