⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23014677 | 0.88 | KDM4E (0.46) | — | |
| SCHEMBL26247584 | 0.79 | — | — | |
| SCHEMBL897672 | 0.79 | — | — | |
| SCHEMBL9188293 | 0.79 | — | — | |
| SCHEMBL26247580 | 0.79 | — | — | |
| SCHEMBL26247587 | 0.79 | — | — | |
| SCHEMBL894866 | 0.79 | — | — | |
| SCHEMBL30585369 | 0.79 | — | — | |
| SCHEMBL14882255 | 0.79 | PTPN1 (0.51) | — | |
| SCHEMBL7189417 | 0.78 | GLO1 (0.67) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12540115-B2 | Inhibitors of phospholipid synthesis and methods of use | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2026-02-03 | — | — | US | disclosed |
| US-20220315528-A1 | INHIBITORS OF PHOSPHOLIPID SYNTHESIS AND METHODS OF USE | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2022-10-06 | — | — | US | disclosed |
| WO-2021035031-A1 | INHIBITORS OF PHOSPHOLIPID SYNTHESIS AND METHODS OF USE | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2021-02-25 | — | — | WO | disclosed |