Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 1/20 | 0.42 |
| ▸ | SGPL1 | O95470 | 2/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.35 |
| ▸ | GPR6 | P46095 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | CCR6 | P51684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2301483 | 1.00 | SMO (0.42) | SMOSGPL1HCRTR1HCRTR2PDE4B | |
| SCHEMBL12244267 | 1.00 | SMO (0.42) | SMOSGPL1HCRTR1HCRTR2PDE4B | |
| SCHEMBL14145917 | 0.87 | HCRTR1 (0.41) | SMOHCRTR1HCRTR2 | |
| SCHEMBL12243613 | 0.87 | SMO (0.40) | SMOSGPL1HCRTR1HCRTR2TIPARP | |
| SCHEMBL12222741 | 0.87 | PDE4B (0.38) | SMOPDE4BRETPANK3GPR119 | |
| SCHEMBL10107157 | 0.86 | HCRTR1 (0.46) | SMOHCRTR1HCRTR2GPR119 | |
| SCHEMBL382980 | 0.86 | HCRTR1 (0.46) | SMOHCRTR1HCRTR2GPR119 | |
| SCHEMBL12243614 | 0.84 | HCRTR1 (0.37) | SMOSGPL1HCRTR1HCRTR2PDE4B | |
| SCHEMBL1726594 | 0.84 | HCRTR1 (0.37) | SMOSGPL1HCRTR1HCRTR2PDE4B | |
| SCHEMBL1726595 | 0.84 | HCRTR1 (0.37) | SMOSGPL1HCRTR1HCRTR2PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8697867-B2 | Cross-linked cyclic amine compounds and agents for pest control | NIPPON SODA CO., LTD. (JP) | 2014-04-15 | — | — | US | disclosed |
| US-20130331569-A1 | CROSS-LINKED CYCLIC AMINE COMPOUNDS AND AGENTS FOR PEST CONTROL | NIPPON SODA CO., LTD. (JP) | 2013-12-12 | — | — | US | disclosed |
| US-8536340-B2 | Cross-linked cyclic amine compounds and agents for pest control | NIPPON SODA CO., LTD. (JP) | 2013-09-17 | — | — | US | disclosed |
| US-8338607-B2 | Cyclic amine compounds and agents for pest control | NIPPON SODA CO., LTD. (JP) | 2012-12-25 | — | — | US | disclosed |
| US-20110257389-A1 | CROSS-LINKED CYCLIC AMINE COMPOUNDS AND AGENTS FOR PEST CONTROL | NIPPON SODA CO., LTD. (JP) | 2011-10-20 | — | — | US | disclosed |
| US-7999102-B2 | Cross-linked cyclic amine compounds and agents for pest control | NIPPON SODA CO., LTD. (JP) | 2011-08-16 | — | — | US | disclosed |
| US-20090318694-A1 | Cross-Linked Amine Compounds and Agents for Pest Control | NIPPON SODA CO., LTD. (JP) | 2009-12-24 | — | — | US | disclosed |
| US-20090259046-A1 | Cyclic Amine Compounds and Agents for Pest Control | NIPPON SODA CO., LTD. (JP) | 2009-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110257389-A1 | CROSS-LINKED CYCLIC AMINE COMPOUNDS AND AGENTS FOR PEST CONTROL | CYCS, NPY1R, CYBB | SMO 2441/4885SGPL1 2579/4885HCRTR1 84/4885 |
| US-20090259046-A1 | Cyclic Amine Compounds and Agents for Pest Control | NPR1, CYCS, CYC1 | SMO 3364/4885SGPL1 1689/4885HCRTR1 115/4885 |
| US-20130331569-A1 | CROSS-LINKED CYCLIC AMINE COMPOUNDS AND AGENTS FOR PEST CONTROL | CYCS, NPY1R, CYBB | SMO 2441/4885SGPL1 2579/4885HCRTR1 84/4885 |
| US-20090318694-A1 | Cross-Linked Amine Compounds and Agents for Pest Control | CYCS, NPY1R, CYBB | SMO 2707/4885SGPL1 2460/4885HCRTR1 100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.