Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | GOT1 | P17174 | 1/20 | 0.42 |
| ▸ | GLS | O94925 | 2/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29760793 | 0.84 | GOT1 (0.52) | GOT1GLSPIM1 | |
| Hydrochloric Acid SCHEMBL2369142 | 0.83 | GOT1 (0.50) | GOT1GLSPIM1 | |
| SCHEMBL30488505 | 0.82 | KAT2B (0.50) | KAT2B | |
| SCHEMBL28654783 | 0.82 | KAT2B (0.50) | KAT2B | |
| SCHEMBL12440506 | 0.80 | NOS2 (0.62) | HRH4POLBNOS2IKBKBRET | |
| Hydrochloric Acid SCHEMBL27710837 | 0.79 | NOS2 (0.60) | HRH4POLBNOS2IKBKBRET | |
| SCHEMBL30099780 | 0.77 | HRH3 (0.50) | GOT1RET | |
| SCHEMBL4715270 | 0.77 | GOT1 (0.48) | GOT1RETPIM1CDK2 | |
| SCHEMBL5001464 | 0.77 | HRH3 (0.50) | GOT1RET | |
| SCHEMBL4715269 | 0.77 | GOT1 (0.48) | GOT1RETPIM1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011101640-A1 | FUSED HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF MALARIA | MEDICAL RESEARCH COUNCIL TECHNOLOGY (GB) | 2011-08-25 | — | — | WO | disclosed |