Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ERN1 | O75460 | 2/20 | 0.46 |
| ▸ | ACVR1 | Q04771 | 3/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.39 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | BPTF | Q12830 | 1/20 | 0.38 |
| ▸ | ATR | Q13535 | 1/20 | 0.38 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24475637 | 0.96 | POLB (0.44) | NPC1POLBRAB9ACYP3A4ERN1 | |
| SCHEMBL24475593 | 0.91 | CYP3A4 (0.44) | NPC1POLBRAB9ACYP3A4ERN1 | |
| SCHEMBL23016043 | 0.91 | POLB (0.51) | NPC1POLBRAB9ACYP3A4ERN1 | |
| SCHEMBL23016135 | 0.89 | NPC1 (0.49) | NPC1POLBRAB9ACYP3A4ERN1 | |
| SCHEMBL23016200 | 0.88 | NPC1 (0.44) | NPC1POLBRAB9ACYP3A4ERN1 | |
| SCHEMBL24475636 | 0.88 | POLB (0.48) | NPC1POLBRAB9ACYP3A4ERN1 | |
| SCHEMBL23016046 | 0.88 | NPC1 (0.46) | NPC1POLBRAB9ACYP3A4ERN1 | |
| SCHEMBL22281645 | 0.86 | NPC1 (0.46) | NPC1POLBRAB9ACYP3A4ERN1 | |
| SCHEMBL23016210 | 0.85 | NPC1 (0.44) | NPC1POLBRAB9ACYP3A4DYRK1A | |
| SCHEMBL23016198 | 0.85 | NPC1 (0.46) | NPC1POLBRAB9ACYP3A4DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10930857-B2 | Heterocyclic compound and organic light emitting device using same | LT MATERIALS CO., LTD. (KR) | 2021-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10930857-B2 | Heterocyclic compound and organic light emitting device using same | CRY1, CRY2, CYBA | NPC1 4299/4885POLB 699/4885RAB9A 3913/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.