Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 2/20 | 0.41 |
| ▸ | CCR5 | P51681 | 2/20 | 0.41 |
| ▸ | CCR8 | P51685 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TOP1 | P11387 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23016087 | 0.94 | NPC1 (0.45) | NPC1RAB9APOLBCCR1CCR5 | |
| SCHEMBL23016197 | 0.92 | TOP1 (0.40) | NPC1RAB9APOLBCCR1CCR5 | |
| SCHEMBL23016194 | 0.91 | NPC1 (0.42) | NPC1RAB9APOLBCCR1CCR5 | |
| SCHEMBL24475701 | 0.91 | NPC1 (0.42) | NPC1RAB9APOLBCCR1CCR5 | |
| SCHEMBL23016179 | 0.91 | NPC1 (0.42) | NPC1RAB9APOLBCCR1CCR5 | |
| SCHEMBL23016261 | 0.91 | TOP1 (0.50) | NPC1RAB9APOLBCCR1CCR5 | |
| SCHEMBL23016311 | 0.91 | NPC1 (0.51) | NPC1RAB9APOLBCCR1CCR5 | |
| SCHEMBL23016227 | 0.91 | NPC1 (0.44) | NPC1RAB9APOLBCCR1CCR5 | |
| SCHEMBL23016174 | 0.89 | TOP1 (0.49) | NPC1RAB9APOLBCCR1CCR5 | |
| SCHEMBL23016245 | 0.89 | TOP1 (0.46) | NPC1RAB9APOLBCCR1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10930857-B2 | Heterocyclic compound and organic light emitting device using same | LT MATERIALS CO., LTD. (KR) | 2021-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10930857-B2 | Heterocyclic compound and organic light emitting device using same | CRY1, CRY2, CYBA | NPC1 4299/4885RAB9A 3913/4885POLB 699/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.