Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.46 |
| ▸ | SELL | P14151 | 1/20 | 0.45 |
| ▸ | SELP | P16109 | 1/20 | 0.45 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.44 |
| ▸ | MYC | P01106 | 2/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 2/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.40 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.40 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.40 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10901788 | 0.86 | GABRP (0.43) | CSNK2A1MYCGABRPGABRDGABRA1 | |
| SCHEMBL12501719 | 0.85 | MCL1 (0.47) | CSNK2A1SELLSELPSLC22A6SLC22A8 | |
| SCHEMBL28670020 | 0.85 | CSNK2A1 (0.46) | CSNK2A1SELLSELPSLC22A6SLC22A8 | |
| SCHEMBL542401 | 0.84 | SELL (0.48) | CSNK2A1SELLSELPMCL1KLKB1 | |
| SCHEMBL31668786 | 0.84 | SELL (0.48) | CSNK2A1SELLSELPMCL1KLKB1 | |
| SCHEMBL28623909 | 0.84 | KAT8 (0.50) | CSNK2A1SELLSELPSLC22A6SLC22A8 | |
| SCHEMBL7072975 | 0.82 | GABRP (0.41) | MYCMCL1GABRPGABRDGABRA1 | |
| SCHEMBL39790 | 0.82 | SELL (0.57) | CSNK2A1SELLSELPMCL1KLKB1 | |
| SCHEMBL294836 | 0.81 | CYP1A2 (0.50) | SELLSELPGABRPGABRDGABRA1 | |
| SCHEMBL18419577 | 0.81 | SELL (0.45) | CSNK2A1SELLSELPMCL1KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113748021-A | Method for producing liquid crystal polyester processed product | 本州化学工业株式会社 | 2021-12-03 | — | — | CN | disclosed |
| CN-113285024-A | Semiconductor device having quantum dots, display device, imaging system, and moving object | 佳能株式会社 | 2021-08-20 | — | — | CN | disclosed |
| EP-2349983-B1 | DIFLUORPHENYL DIACYLHYDRAZIDE DERIVATES | MERCK PATENT GMBH (DE) | 2016-09-14 | — | — | EP | disclosed |
| EP-2349983-B1 | DIFLUORPHENYL DIACYLHYDRAZIDE DERIVATES | MERCK PATENT GMBH (DE) | 2016-09-14 | — | — | EP | disclosed |
| US-8492440-B2 | Difluorophenyldiacylhydrazide derivatives | MERCK PATENT GMBH (DE) | 2013-07-23 | — | — | US | disclosed |
| US-8492440-B2 | Difluorophenyldiacylhydrazide derivatives | MERCK PATENT GMBH (DE) | 2013-07-23 | — | — | US | disclosed |
| US-8492440-B2 | Difluorophenyldiacylhydrazide derivatives | MERCK PATENT GMBH (DE) | 2013-07-23 | — | — | US | disclosed |
| US-20110224302-A1 | DIFLUOROPHENYLDIACYLHYDRAZIDE DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-09-15 | — | — | US | disclosed |
| US-20110224302-A1 | DIFLUOROPHENYLDIACYLHYDRAZIDE DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-09-15 | — | — | US | disclosed |
| US-20110224302-A1 | DIFLUOROPHENYLDIACYLHYDRAZIDE DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-09-15 | — | — | US | disclosed |
| EP-2349983-A2 | DIFLUORPHENYL DIACYLHYDRAZIDE DERIVATES | Merck Patent GmbH (DE) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010060522-A2 | DIFLUORPHENYL DIACYLHYDRAZIDE DERIVATES | MERCK PATENT GMBH (DE) | 2010-06-03 | — | — | WO | disclosed |
| WO-2010060522-A2 | DIFLUORPHENYL DIACYLHYDRAZIDE DERIVATES | MERCK PATENT GMBH (DE) | 2010-06-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110224302-A1 | DIFLUOROPHENYLDIACYLHYDRAZIDE DERIVATIVES | FGFR1, PKD1, AGTR1 | CSNK2A1 1235/4885SELL 3355/4885SELP 3861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.