Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 14/20 | 0.62 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5638416 | 0.79 | TUBB1 (0.46) | NAMPTGAA | |
| SCHEMBL31757616 | 0.77 | EPHX2 (0.63) | EPHX2ABL1PDE2ATRPA1 | |
| SCHEMBL28105814 | 0.77 | EPHX2 (0.63) | EPHX2ABL1PDE2ATRPA1KDR | |
| SCHEMBL25069025 | 0.77 | EPHX2 (0.63) | EPHX2ABL1PDE2ATRPA1 | |
| SCHEMBL17130390 | 0.77 | EPHX2 (1.00) | EPHX2ABL1KDR | |
| SCHEMBL23088133 | 0.75 | EPHX2 (0.79) | EPHX2ABL1KDR | |
| SCHEMBL19287089 | 0.75 | KIF11 (0.50) | EPHX2 | |
| SCHEMBL23419127 | 0.74 | EPHX2 (0.77) | EPHX2ABL1 | |
| SCHEMBL30441095 | 0.74 | EPHX2 (0.77) | EPHX2ABL1PDE2A | |
| SCHEMBL241795 | 0.74 | RAB9A (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3129023-B1 | POTENT SOLUBLE EPOXIDE HYDROLASE INHIBITORS | EICOSIS LLC (US) | 2021-02-24 | — | — | EP | disclosed |