Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 10/20 | 0.56 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MYC | P01106 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23020185 | 0.99 | GRM5 (0.55) | GRM5CLK4ABCG2ALDH1A1MAPT | |
| SCHEMBL23020186 | 0.99 | GRM5 (0.55) | GRM5CLK4ABCG2ALDH1A1MAPT | |
| SCHEMBL23020146 | 0.96 | GRM5 (0.53) | GRM5CLK4ABCG2ALDH1A1LMNA | |
| SCHEMBL23020433 | 0.96 | GRM5 (0.53) | GRM5CLK4ABCG2ALDH1A1LMNA | |
| SCHEMBL23020096 | 0.96 | GRM5 (0.53) | GRM5CLK4ABCG2ALDH1A1LMNA | |
| SCHEMBL23020094 | 0.96 | GRM5 (0.53) | GRM5CLK4ABCG2ALDH1A1LMNA | |
| SCHEMBL19020374 | 0.96 | GRM5 (0.60) | GRM5CLK4KDM4EKCNH2TDP1 | |
| SCHEMBL23020311 | 0.94 | GRM5 (0.51) | GRM5CLK4ABCG2ALDH1A1MAPT | |
| SCHEMBL23020407 | 0.94 | GRM5 (0.51) | GRM5CLK4ABCG2ALDH1A1MAPT | |
| SCHEMBL23020137 | 0.92 | GRM5 (0.49) | GRM5CLK4ABCG2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3392242-B1 | NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME | LG CHEMICAL LTD (KR) | 2021-02-24 | — | — | EP | disclosed |