Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | CNR2 | P34972 | 1/20 | 0.54 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | FNTA | P49354 | 1/20 | 0.45 |
| ▸ | FNTB | P49356 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9391336 | 0.91 | CES2 (0.50) | CNR2MEN1KMT2ARAB9AL3MBTL1 | |
| SCHEMBL10882007 | 0.87 | BRD4 (0.63) | BRD4MEN1KMT2ATDP1HDAC4 | |
| SCHEMBL7973591 | 0.86 | HPGD (0.58) | HPGDCNR2MEN1KMT2AUTS2R | |
| SCHEMBL6755554 | 0.84 | ACP3 (0.59) | CNR2MEN1KMT2AGAARAB9A | |
| SCHEMBL3693512 | 0.81 | BRD4 (0.54) | HPGDCNR2BRD4MEN1KMT2A | |
| Acetic Acid SCHEMBL9138173 | 0.81 | HPGD (0.70) | HPGDCNR2MEN1KMT2AMAOB | |
| SCHEMBL28419252 | 0.79 | BRD4 (0.55) | CNR2BRD4MEN1KMT2ATDP1 | |
| SCHEMBL11431074 | 0.79 | HPGD (0.58) | HPGDCNR2MEN1KMT2AUTS2R | |
| SCHEMBL2302536 | 0.78 | BRD4 (0.53) | BRD4RAB9AHDAC4HDAC7HDAC5 | |
| SCHEMBL16807279 | 0.78 | HPGD (0.57) | HPGDCNR2MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2349999-A1 | ALLOSTERIC PROTEIN KINASE MODULATORS | Universität des Saarlandes (DE) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010043711-A1 | ALLOSTERIC PROTEIN KINASE MODULATORS | UNIVERSITAET DES SAARLANDES (DE) | 2010-04-22 | — | — | WO | disclosed |