Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | CNR2 | P34972 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | FNTA | P49354 | 1/20 | 0.48 |
| ▸ | FNTB | P49356 | 1/20 | 0.48 |
| ▸ | LDHA | P00338 | 1/20 | 0.47 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.46 |
| ▸ | CDC42 | P60953 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7044804 | 0.91 | LDHA (0.55) | CNR2LDHAMAPTPTGS2PTGS1 | |
| SCHEMBL2302103 | 0.86 | HPGD (0.58) | HPGDCNR2KMT2AMEN1FNTA | |
| SCHEMBL11431074 | 0.86 | HPGD (0.58) | HPGDCNR2KMT2AMEN1FNTA | |
| SCHEMBL1716394 | 0.85 | ACP3 (0.61) | CNR2KMT2AMEN1LDHAPOLB | |
| SCHEMBL467546 | 0.84 | HDAC4 (0.59) | CNR2KMT2AMEN1LMNAPOLB | |
| SCHEMBL31560153 | 0.84 | LTA4H (0.53) | CNR2KMT2AMEN1LDHAMAPT | |
| Hydrochloric Acid SCHEMBL933980 | 0.82 | HDAC4 (0.57) | CNR2KMT2AMEN1LMNAPOLB | |
| SCHEMBL934527 | 0.81 | PPARG (0.55) | HPGDCNR2KMT2AMEN1FNTA | |
| SCHEMBL16807279 | 0.81 | HPGD (0.57) | HPGDCNR2KMT2AMEN1TDP1 | |
| Acetic Acid SCHEMBL9138173 | 0.81 | HPGD (0.70) | HPGDCNR2KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001002364-A1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 2001-01-11 | — | — | WO | disclosed |