Pyridine

Pyridine

SCHEMBL4753513

c1ccc(CNCc2ccccn2)nc1.c1ccncc1

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.61
MAOA P21397 2/20 0.60
MAOB P27338 2/20 0.60
KDM4E B2RXH2 4/20 0.57
SMN1; SMN2 Q16637 1/20 0.53
SIRT2 Q8IXJ6 1/20 0.53
ALDH1A1 P00352 4/20 0.53
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
L3MBTL1 Q9Y468 3/20 0.50
POLB P06746 1/20 0.49
NPC1 O15118 1/20 0.49
RAB9A P51151 1/20 0.49
CCR5 P51681 1/20 0.48
SCN8A Q9UQD0 1/20 0.47
ALOX15 P16050 1/20 0.47
TSHR P16473 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29438821 0.91 CHRM2 (0.70) CHRM2MAOAMAOBKDM4ESMN1; SMN2
SCHEMBL230222 0.91 CHRM2 (0.70) CHRM2MAOAMAOBKDM4ESMN1; SMN2
SCHEMBL317984 0.89 CHRM2 (0.68) CHRM2MAOAMAOBKDM4ESMN1; SMN2
SCHEMBL18493706 0.89 CHRM2 (0.68) CHRM2MAOAMAOBKDM4ESMN1; SMN2
Zinc Ion SCHEMBL30442739 0.89 CHRM2 (0.68) CHRM2MAOAMAOBKDM4ESMN1; SMN2
SCHEMBL25211342 0.89 CHRM2 (0.68) CHRM2MAOAMAOBKDM4ESMN1; SMN2
Zinc Ion SCHEMBL30205248 0.89 CHRM2 (0.68) CHRM2MAOAMAOBKDM4ESMN1; SMN2
SCHEMBL2947235 0.86 ALDH1A1 (0.63) CHRM2MAOAMAOBKDM4ESMN1; SMN2
SCHEMBL5569292 0.83 L3MBTL1 (0.62) CHRM2MAOAMAOBKDM4ESMN1; SMN2
SCHEMBL9777455 0.83 CHRM2 (0.61) CHRM2MAOAMAOBKDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008139204-A2 FUNCTIONAL GROUP IMPRINTED POLYMERS IMPERIAL INNOVATIONS LTD (GB) 2008-11-20 WO claimed
WO-2008139204-A2 FUNCTIONAL GROUP IMPRINTED POLYMERS IMPERIAL INNOVATIONS LTD (GB) 2008-11-20 WO disclosed