Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | ACLY | P53396 | 2/20 | 0.53 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.53 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.52 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | TCF4 | P15884 | 1/20 | 0.48 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22653516 | 0.88 | ERAP1 (0.66) | ALDH1A1TSHRACLYERAP1LMNA | |
| SCHEMBL29669997 | 0.86 | NPSR1 (0.49) | CYP2C9ALDH1A1TSHRNPSR1ERAP1 | |
| SCHEMBL22891786 | 0.86 | NPSR1 (0.49) | CYP2C9ALDH1A1TSHRNPSR1ERAP1 | |
| SCHEMBL7567314 | 0.81 | NPSR1 (0.59) | CYP2C9ALDH1A1NPSR1ACLYSLC40A1 | |
| SCHEMBL19065100 | 0.80 | GAA (0.64) | ALDH1A1TSHRLMNAHSD17B2POLB | |
| SCHEMBL22891787 | 0.80 | NPSR1 (0.49) | ALDH1A1NPSR1ERAP1LMNAMCL1 | |
| SCHEMBL7458365 | 0.79 | MEN1 (0.64) | PKMACLYERAP1GAAKMT2A | |
| SCHEMBL29670020 | 0.79 | ERAP1 (0.46) | ALDH1A1NPSR1ERAP1LMNAMAPK1 | |
| SCHEMBL7570517 | 0.78 | CYP2C9 (0.61) | CYP2C9ALDH1A1TSHRNPSR1PKM | |
| SCHEMBL22498190 | 0.78 | CACNA1B (0.56) | ALDH1A1NPSR1POLBGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240016768-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING PHENYLSULFONAMIDES, AND THEIR THERAPEUTIC APPLICATIONS | CURA THERAPEUTICS, LLC | 2024-01-18 | — | — | US | disclosed |
| US-11701334-B2 | Pharmaceutical compositions comprising phenylsulfonamides, and their therapeutic applications | CURA THERAPEUTICS, LLC (US) | 2023-07-18 | — | — | US | disclosed |
| US-20210052525-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING PHENYLSULFONAMIDES, AND THEIR THERAPEUTIC APPLICATIONS | CURA THERAPEUTICS, LLC | 2021-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210052525-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING PHENYLSULFONAMIDES, AND THEIR THERAPEUTIC APPLICATIONS | MAPT, PSEN1, PSEN2 | CYP2C9 426/4885ALDH1A1 2458/4885TSHR 3698/4885 |
| US-20240016768-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING PHENYLSULFONAMIDES, AND THEIR THERAPEUTIC APPLICATIONS | MAPT, PSEN1, PSEN2 | CYP2C9 426/4885ALDH1A1 2458/4885TSHR 3698/4885 |
| US-11701334-B2 | Pharmaceutical compositions comprising phenylsulfonamides, and their therapeutic applications | MAPT, PSEN1, PSEN2 | CYP2C9 426/4885ALDH1A1 2458/4885TSHR 3698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.