Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | SLC20A2 | Q08357 | 1/20 | 0.52 |
| ▸ | SLC20A1 | Q8WUM9 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | MMP1 | P03956 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | MMP8 | P22894 | 1/20 | 0.52 |
| ▸ | MMP13 | P45452 | 1/20 | 0.52 |
| ▸ | ACLY | P53396 | 3/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.50 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.50 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.49 |
| ▸ | CCR2 | P41597 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7570517 | 0.94 | CYP2C9 (0.61) | NPSR1GAAMEN1KMT2ASLC20A2 | |
| SCHEMBL7578595 | 0.90 | NPSR1 (0.72) | NPSR1GAAMEN1KMT2ASLC20A2 | |
| SCHEMBL7572555 | 0.86 | CYP2C9 (0.60) | NPSR1MEN1KMT2AACLYCYP2C9 | |
| SCHEMBL19065100 | 0.84 | GAA (0.64) | GAAMEN1KMT2ACA1CA2 | |
| SCHEMBL7569668 | 0.82 | KMT2A (0.76) | NPSR1GAAMEN1KMT2ASLC20A2 | |
| SCHEMBL7572438 | 0.81 | SLC20A2 (0.63) | NPSR1GAAMEN1KMT2ASLC20A2 | |
| SCHEMBL23022352 | 0.81 | CYP2C9 (0.57) | NPSR1GAAMEN1KMT2AACLY | |
| SCHEMBL7572561 | 0.80 | NPSR1 (0.66) | NPSR1GAAMEN1KMT2ASLC20A2 | |
| SCHEMBL22498190 | 0.80 | CACNA1B (0.56) | NPSR1GAAMEN1KMT2ACA1 | |
| SCHEMBL29528521 | 0.80 | CACNA1B (0.56) | NPSR1GAAMEN1KMT2ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002083629-A1 | BISSULFONAMIDE DERIVATIVES AS INHIBITORS OF DEHYDROQUINATE SYNTHETASES AND TYPE II DEHYDROQUINASES | ARROW THERAPEUTICS LIMITED (GB) | 2002-10-24 | — | — | WO | disclosed |
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |