Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 5/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.56 |
| ▸ | TCF4 | P15884 | 1/20 | 0.56 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.56 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.55 |
| ▸ | CDK1 | P06493 | 1/20 | 0.55 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.55 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.55 |
| ▸ | CDK2 | P24941 | 1/20 | 0.55 |
| ▸ | CDK7 | P50613 | 1/20 | 0.55 |
| ▸ | CCNH | P51946 | 1/20 | 0.55 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7567314 | 0.94 | NPSR1 (0.59) | CYP2C9NPSR1ALDH1A1LMNAMEN1 | |
| SCHEMBL7578595 | 0.86 | NPSR1 (0.72) | NPSR1ALDH1A1LMNAKDM4EMEN1 | |
| SCHEMBL7572555 | 0.85 | CYP2C9 (0.60) | CYP2C9NPSR1ALDH1A1LMNAKDM4E | |
| SCHEMBL7571635 | 0.85 | FFAR1 (0.66) | NPSR1FFAR4FFAR1CDK1CCNB1 | |
| SCHEMBL7573928 | 0.85 | CYP2C9 (0.82) | CYP2C9NPSR1TCF4CTNNB1FFAR4 | |
| SCHEMBL7572541 | 0.82 | FFAR1 (0.62) | NPSR1FFAR4FFAR1CDK1CCNB1 | |
| SCHEMBL7572374 | 0.79 | NPSR1 (0.58) | CYP2C9NPSR1ALDH1A1LMNAKDM4E | |
| SCHEMBL19065100 | 0.79 | GAA (0.64) | TCF4CTNNB1FFAR4FFAR1CDK1 | |
| SCHEMBL3528690 | 0.79 | KDM1A (0.61) | CYP2C9NPSR1FFAR4FFAR1CDK1 | |
| SCHEMBL23022352 | 0.78 | CYP2C9 (0.57) | CYP2C9NPSR1TCF4CTNNB1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |