Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD44 | P16070 | 1/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10510801 | 0.86 | KCNN4 (0.42) | KCNN4TAAR1MAPK1KMT2AMAPT | |
| SCHEMBL4409081 | 0.82 | CYP3A4 (0.41) | CD44KCNN4TAAR1MAPK1KMT2A | |
| SCHEMBL30606647 | 0.82 | CYP3A4 (0.41) | CD44KCNN4TAAR1MAPK1KMT2A | |
| SCHEMBL3132847 | 0.82 | KCNN4 (0.42) | CD44KCNN4MAPTCYP3A4ALOX15 | |
| SCHEMBL222895 | 0.80 | KCNN4 (0.53) | CD44KCNN4MAPTCYP3A4ALOX15 | |
| Hydrochloric Acid SCHEMBL27897779 | 0.78 | KCNN4 (0.52) | CD44KCNN4MAPTCYP3A4ALOX15 | |
| SCHEMBL10961821 | 0.78 | CD44 (0.36) | CD44KCNN4TAAR1CYP3A4TSHR | |
| SCHEMBL10784751 | 0.78 | CD44 (0.38) | CD44KCNN4TAAR1MAPTCYP3A4 | |
| SCHEMBL8512559 | 0.74 | CD44 (0.48) | CD44CYP3A4ALOX15CASP1CASP7 | |
| SCHEMBL6028201 | 0.74 | CD44 (0.48) | CD44KMT2AMAPTCYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013057069-A1 | POLYCYCLIC AROMATIC POLYAMINES AND METHODS FOR PRODUCTION THEREOF | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-04-25 | — | — | WO | disclosed |
| US-20110190535-A1 | PROCESS FOR PREPARING POLYAROMATIC POLYISOCYANATE COMPOSITIONS | HUNTSMAN INTERNATIONAL LLC (US) | 2011-08-04 | — | — | US | disclosed |
| EP-2183295-A1 | PROCESS FOR PREPARING POLYAROMATIC POLYISOCYANATE COMPOSITIONS | Huntsman International LLC (US) | 2010-05-12 | — | — | EP | disclosed |
| WO-2009024407-A1 | PROCESS FOR PREPARING POLYAROMATIC POLYISOCYANATE COMPOSITIONS | HUNTSMAN INTERNATIONAL LLC (US) | 2009-02-26 | — | — | WO | disclosed |
| EP-0158952-B1 | TRIAMINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS CROSS-LINKING AGENTS OR HARDENERS FOR PLASTIC MATERIALS OR PRECURSORS HAVING EPOXY- OR ISOCYANATE-GROUPS | BAYER AG (DE) | 1988-04-20 | — | — | EP | disclosed |
| US-4675437-A | Cycloaliphatic triisocyanates | BAYER AKTIENGESELLSCHAFT (DE) | 1987-06-23 | — | — | US | disclosed |
| EP-0162346-B1 | TRIISOCYANATES, PROCESS FOR THEIR PRODUCTION, AND THEIR USE IN THE MANUFACTURE OF POLYURETHANES | BAYER AG (DE) | 1987-06-03 | — | — | EP | disclosed |
| US-4613687-A | POLYURETHANES | BAYER AKTIENGESELLSCHAFT (DE) | 1986-09-23 | — | — | US | disclosed |
| US-4603189-A | Triisocyanates and a process for their preparation | BAYER AKTIENGESELLSCHAFT (DE) | 1986-07-29 | — | — | US | disclosed |
| EP-0162346-A1 | Triisocyanates, process for their production, and their use in the manufacture of polyurethanes | BAYER AG (DE) | 1985-11-27 | — | — | EP | disclosed |
| EP-0158952-A2 | Triamines, a process for their preparation and their use as cross-linking agents or hardeners for plastic materials or precursors having epoxy- or isocyanate-groups | BAYER AG (DE) | 1985-10-23 | — | — | EP | disclosed |
| EP-0046917-B1 | POLYISOCYANATE MIXTURES OF THE DIPHENYLMETHANE CLASS, AS WELL AS THEIR USE AS SYNTHESIS COMPONENTS IN THE MANUFACTURE OF POLYURETHANES BY THE ISOCYANATE-POLYADDITION PROCESS | BAYER AG (DE) | 1983-12-07 | — | — | EP | disclosed |
| EP-0046917-A1 | Polyisocyanate mixtures of the diphenylmethane class, as well as their use as synthesis components in the manufacture of polyurethanes by the isocyanate-polyaddition process | BAYER AG (DE) | 1982-03-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110190535-A1 | PROCESS FOR PREPARING POLYAROMATIC POLYISOCYANATE COMPOSITIONS | MAOA, DDC, MAOB | CD44 3067/4885KCNN4 2891/4885TAAR1 196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.