Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | JAK3 | P52333 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23013130 | 0.89 | ALDH1A1 (0.50) | ALDH1A1NPSR1HPGDHSD17B10CYP1A2 | |
| SCHEMBL29703799 | 0.89 | ALDH1A1 (0.50) | ALDH1A1NPSR1HPGDHSD17B10CYP1A2 | |
| SCHEMBL23023704 | 0.86 | CYP1A2 (0.40) | ALDH1A1NPSR1HPGDHSD17B10CYP1A2 | |
| SCHEMBL23013498 | 0.84 | ALDH1A1 (0.46) | ALDH1A1NPSR1HPGDHSD17B10CYP1A2 | |
| SCHEMBL29692671 | 0.84 | ALDH1A1 (0.46) | ALDH1A1NPSR1HPGDHSD17B10CYP1A2 | |
| SCHEMBL25150438 | 0.84 | CYP1A2 (0.65) | ALDH1A1HPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL29692267 | 0.83 | NPC1 (0.51) | ALDH1A1NPSR1HPGDHSD17B10CYP1A2 | |
| SCHEMBL23013917 | 0.83 | NPC1 (0.51) | ALDH1A1NPSR1HPGDHSD17B10CYP1A2 | |
| SCHEMBL23013504 | 0.82 | PDE4A (0.54) | ALDH1A1NPSR1HPGDHSD17B10CYP1A2 | |
| SCHEMBL23013072 | 0.81 | RXFP1 (0.45) | ALDH1A1NPSR1HPGDHSD17B10NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11634425-B2 | Pharmaceutical compounds | PFIZER INC. (US) | 2023-04-25 | — | — | US | disclosed |
| WO-2021032992-A1 | PHARMACEUTICAL COMPOUNDS | ReViral Limited (GB) | 2021-02-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11634425-B2 | Pharmaceutical compounds | GABRA6, CHRNA6, CNR1 | ALDH1A1 3010/4885NPSR1 112/4885HPGD 3197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.