SCHEMBL23027009

SCHEMBL23027009

Ic1nc2ccc3ccccc3c2nc1I

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT5 O14744 1/20 0.49
PRMT3 O60678 1/20 0.49
CARM1 Q86X55 1/20 0.49
EHMT2 Q96KQ7 1/20 0.49
PRMT6 Q96LA8 1/20 0.49
PRMT1 Q99873 1/20 0.49
WDR77 Q9BQA1 1/20 0.49
SLC2A1 P11166 1/20 0.45
ALDH1A1 P00352 2/20 0.44
HSD17B10 Q99714 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
CYP2A6 P11509 1/20 0.44
TSHR P16473 1/20 0.44
CYP3A4 P08684 1/20 0.44
MAOA P21397 1/20 0.41
HPRT1 P00492 1/20 0.41
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
TYMS P04818 2/20 0.39
LMNA P02545 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5470832 0.84 PRMT5 (0.56) PRMT5PRMT3CARM1EHMT2PRMT6
SCHEMBL5473804 0.82 PRMT5 (0.59) PRMT5PRMT3CARM1EHMT2PRMT6
SCHEMBL24813630 0.82 LMNA (0.42) PRMT5PRMT3CARM1EHMT2PRMT6
Benzo[A]Phenazine SCHEMBL29618896 0.78 ALDH1A1 (0.55) PRMT5PRMT3CARM1EHMT2PRMT6
Benzo[A]Phenazine SCHEMBL88133 0.78 ALDH1A1 (0.55) PRMT5PRMT3CARM1EHMT2PRMT6
SCHEMBL13156514 0.77 PRMT5 (0.54) PRMT5PRMT3CARM1EHMT2PRMT6
SCHEMBL11694058 0.77 PRMT5 (0.54) PRMT5PRMT3CARM1EHMT2PRMT6
SCHEMBL13156543 0.77 PRMT5 (0.54) PRMT5PRMT3CARM1EHMT2PRMT6
SCHEMBL5478688 0.75 NQO2 (0.54) PRMT5PRMT3CARM1EHMT2PRMT6
SCHEMBL19520619 0.75 TDP1 (0.50) PRMT5PRMT3CARM1EHMT2PRMT6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021034017-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME 주식회사 엘지화학 2021-02-25 WO disclosed